PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24218884-4 2013 Comparative Q-PCR was utilized to investigate target gene (P66SHC, EP300, HDAC1) expressions respectively in H2O2 treated groups and normal cell groups. Hydrogen Peroxide 109-113 E1A binding protein p300 Homo sapiens 67-72 30805890-5 2019 Furthermore, the expression levels of TRP-1, TRP-2 and p300 were reduced in both senescent cells and the H2O2-treated cells, but that of SIRT-1 was inverted compared with young cells. Hydrogen Peroxide 105-109 E1A binding protein p300 Homo sapiens 55-59 29579543-8 2018 Furthermore, the expression levels of p300, Ac-p53, p53, p-p21 and p16 were significantly increased in senescent and H2O2-induced cells compared to young cells. Hydrogen Peroxide 117-121 E1A binding protein p300 Homo sapiens 38-42 23141413-8 2013 Meanwhile, H(2)O(2) induced the upregulation of histone acetyltransferases p300/cAMP-response element binding protein (p300/CBP) and downregulation of histone deacetylases. Hydrogen Peroxide 11-19 E1A binding protein p300 Homo sapiens 119-127