PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9469830-0 1998 Substrate specificity of the Ogg1 protein of Saccharomyces cerevisiae: excision of guanine lesions produced in DNA by ionizing radiation- or hydrogen peroxide/metal ion-generated free radicals. Hydrogen Peroxide 141-158 8-oxoguanine glycosylase OGG1 Saccharomyces cerevisiae S288C 29-33 15449310-0 2004 Role of OGG1 and NTG2 in the repair of oxidative DNA damage and mutagenesis induced by hydrogen peroxide in Saccharomyces cerevisiae: relationships with transition metals iron and copper. Hydrogen Peroxide 87-104 8-oxoguanine glycosylase OGG1 Saccharomyces cerevisiae S288C 8-12 15449310-5 2004 In the present study we evaluated the role of S. cerevisiae OGG1 and NTG2 genes in the repair of oxidative lesions induced by high H2O2 concentrations (5-100 mM for 20 min), followed by catalase treatment (500 IU/ml). Hydrogen Peroxide 131-135 8-oxoguanine glycosylase OGG1 Saccharomyces cerevisiae S288C 60-64 15449310-6 2004 In these conditions, the ogg1 mutant was more sensitive than the WT strain to H2O2 (concentration 40-60 mM). Hydrogen Peroxide 78-82 8-oxoguanine glycosylase OGG1 Saccharomyces cerevisiae S288C 25-29 15449310-7 2004 Unexpectedly, the inactivation of NTG2 in an ogg1 background was able to suppress both sensitivity and mutagenesis induced by H2O2. Hydrogen Peroxide 126-130 8-oxoguanine glycosylase OGG1 Saccharomyces cerevisiae S288C 45-49 15449310-10 2004 The roles of OGG1 and NTG2 genes in the repair of lethal and mutagenic oxidative lesions induced by H2O2 and their relationships with iron and copper ions are discussed. Hydrogen Peroxide 100-104 8-oxoguanine glycosylase OGG1 Saccharomyces cerevisiae S288C 13-17