PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16839682-4 2007 However, the Fenton"s reagent utilizing H2O2/Fe2+ resulted in the highest color, TOC and AOX removals under acidic conditions when compared with the other AOPs tested. Hydrogen Peroxide 40-44 acyl-CoA oxidase 1 Homo sapiens 89-92 19337927-5 2009 Hydrogen peroxide dose and pH were the most effective parameters for pesticide removal while hydrogen peroxide dose had the most significant effect on AOX removal (dehalogenation). Hydrogen Peroxide 93-110 acyl-CoA oxidase 1 Homo sapiens 151-154 19337927-8 2009 The optimal H(2)O(2)/pH/diuron ratio resulting in the maximum pesticide (100%), TOC (82%) and AOX (95%) removal was found to be 340/8/10. Hydrogen Peroxide 12-20 acyl-CoA oxidase 1 Homo sapiens 94-97 17531285-6 2007 Diuron concentration had a more profound effect than H(2)O(2) and Fe(II) in removal of diuron, TOC and AOX from the aqueous solution. Hydrogen Peroxide 53-61 acyl-CoA oxidase 1 Homo sapiens 103-106 10493957-0 1999 Neoplastic conversion of human urothelial cells in vitro by overexpression of H2O2-generating peroxisomal fatty acyl CoA oxidase. Hydrogen Peroxide 78-82 acyl-CoA oxidase 1 Homo sapiens 112-128 12948743-7 2003 In addition, we found in skin fibroblasts from D-BP-deficient patients an imbalance between the activities of the peroxisomal H(2)O(2)-generating straight-chain acyl-CoA oxidase (SCOX) and the peroxisomal H(2)O(2)-degrading enzyme catalase. Hydrogen Peroxide 126-134 acyl-CoA oxidase 1 Homo sapiens 146-177 12948743-7 2003 In addition, we found in skin fibroblasts from D-BP-deficient patients an imbalance between the activities of the peroxisomal H(2)O(2)-generating straight-chain acyl-CoA oxidase (SCOX) and the peroxisomal H(2)O(2)-degrading enzyme catalase. Hydrogen Peroxide 126-134 acyl-CoA oxidase 1 Homo sapiens 179-183 12948743-7 2003 In addition, we found in skin fibroblasts from D-BP-deficient patients an imbalance between the activities of the peroxisomal H(2)O(2)-generating straight-chain acyl-CoA oxidase (SCOX) and the peroxisomal H(2)O(2)-degrading enzyme catalase. Hydrogen Peroxide 205-213 acyl-CoA oxidase 1 Homo sapiens 179-183 8159712-1 1994 Peroxisomal acyl-CoA oxidase (ACOX; EC 1.3.3.6) is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs, and it donates electrons directly to molecular oxygen, thereby producing H2O2. Hydrogen Peroxide 252-256 acyl-CoA oxidase 1 Homo sapiens 12-28 7876265-2 1995 The palmitoyl-CoA oxidase (ACOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Hydrogen Peroxide 176-180 acyl-CoA oxidase 1 Homo sapiens 4-25 7876265-2 1995 The palmitoyl-CoA oxidase (ACOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Hydrogen Peroxide 176-180 acyl-CoA oxidase 1 Homo sapiens 27-31 7876265-3 1995 The inducibility of this H2O2-generating ACOX in rat and mouse liver by peroxisome proliferators and the postulated role of the resulting oxidative stress in hepatocarcinogenesis generated interest in characterizing the structure and function of human ACOX. Hydrogen Peroxide 25-29 acyl-CoA oxidase 1 Homo sapiens 41-45 7876265-3 1995 The inducibility of this H2O2-generating ACOX in rat and mouse liver by peroxisome proliferators and the postulated role of the resulting oxidative stress in hepatocarcinogenesis generated interest in characterizing the structure and function of human ACOX. Hydrogen Peroxide 25-29 acyl-CoA oxidase 1 Homo sapiens 252-256 8159712-1 1994 Peroxisomal acyl-CoA oxidase (ACOX; EC 1.3.3.6) is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs, and it donates electrons directly to molecular oxygen, thereby producing H2O2. Hydrogen Peroxide 252-256 acyl-CoA oxidase 1 Homo sapiens 30-34 8159712-2 1994 The discovery of carcinogenic peroxisome proliferators, which markedly increase the levels of this H2O2-producing ACOX in rat and mouse liver, generated interest in peroxisomal beta-oxidation system genes. Hydrogen Peroxide 99-103 acyl-CoA oxidase 1 Homo sapiens 114-118 29491006-2 2018 Peroxisomal ACOX1 (acyl-CoA oxidase 1) is the first and rate-limiting enzyme in fatty acid beta-oxidation and a major producer of H2O2 ACOX1 dysfunction is linked to peroxisomal disorders and hepatocarcinogenesis. Hydrogen Peroxide 130-134 acyl-CoA oxidase 1 Homo sapiens 12-17 34384852-6 2021 Systematic studies with binary and ternary mixtures containing ascorbate indicated that EOs and neurotransmitters could variably enhance (pro-oxidant, POX) or suppress (anti-oxidant, AOX) the production of H2O2 versus the ascorbate control, depending on the concentration ratios of the components in the mixture. Hydrogen Peroxide 206-210 acyl-CoA oxidase 1 Homo sapiens 183-186 34384852-9 2021 Since the anxiolytic effects of different EOs, including extracts of Lavendula angustifolia (lavender) and Salvia rosmarinus (rosemary), were associated with AOX regulation of H2O2 production by ascorbate, it can be concluded that these anxiolytic effects are potentially related to the AOX properties of EOs. Hydrogen Peroxide 176-180 acyl-CoA oxidase 1 Homo sapiens 158-161 35512582-3 2022 The sensing mechanism of the AOx/CNs functionalized sensor lies in the oxidation reaction of alcohol by AOx and the electrocatalytic oxidation reaction of the generated H2O2. Hydrogen Peroxide 169-173 acyl-CoA oxidase 1 Homo sapiens 29-32 35512582-3 2022 The sensing mechanism of the AOx/CNs functionalized sensor lies in the oxidation reaction of alcohol by AOx and the electrocatalytic oxidation reaction of the generated H2O2. Hydrogen Peroxide 169-173 acyl-CoA oxidase 1 Homo sapiens 104-107 30716345-2 2019 This method involves the use of the AOX enzyme that could specifically oxidize methanol, giving rise to equimolar equivalents each of formaldehyde (HCHO) and hydrogen peroxide (H2O2) as the end products. Hydrogen Peroxide 158-175 acyl-CoA oxidase 1 Homo sapiens 36-39 30716345-2 2019 This method involves the use of the AOX enzyme that could specifically oxidize methanol, giving rise to equimolar equivalents each of formaldehyde (HCHO) and hydrogen peroxide (H2O2) as the end products. Hydrogen Peroxide 177-181 acyl-CoA oxidase 1 Homo sapiens 36-39 32169171-1 2020 ACOX1 (acyl-CoA oxidase 1) encodes the first and rate-limiting enzyme of the very-long-chain fatty acid (VLCFA) beta-oxidation pathway in peroxisomes and leads to H2O2 production. Hydrogen Peroxide 163-167 acyl-CoA oxidase 1 Homo sapiens 0-5 32169171-1 2020 ACOX1 (acyl-CoA oxidase 1) encodes the first and rate-limiting enzyme of the very-long-chain fatty acid (VLCFA) beta-oxidation pathway in peroxisomes and leads to H2O2 production. Hydrogen Peroxide 163-167 acyl-CoA oxidase 1 Homo sapiens 7-25 30187303-7 2019 H2O2 generated during photorespiratory metabolism seems to be an important signal to upregulate CEF or AOX. Hydrogen Peroxide 0-4 acyl-CoA oxidase 1 Homo sapiens 103-106 29491006-2 2018 Peroxisomal ACOX1 (acyl-CoA oxidase 1) is the first and rate-limiting enzyme in fatty acid beta-oxidation and a major producer of H2O2 ACOX1 dysfunction is linked to peroxisomal disorders and hepatocarcinogenesis. Hydrogen Peroxide 130-134 acyl-CoA oxidase 1 Homo sapiens 19-37 29491006-2 2018 Peroxisomal ACOX1 (acyl-CoA oxidase 1) is the first and rate-limiting enzyme in fatty acid beta-oxidation and a major producer of H2O2 ACOX1 dysfunction is linked to peroxisomal disorders and hepatocarcinogenesis. Hydrogen Peroxide 130-134 acyl-CoA oxidase 1 Homo sapiens 135-140 29491006-5 2018 Deletion of SIRT5 increases H2O2 production and oxidative DNA damage, which can be alleviated by ACOX1 knockdown. Hydrogen Peroxide 28-32 acyl-CoA oxidase 1 Homo sapiens 97-102 29964470-3 2016 The results showed that the removal ratios of AOX, chroma and TOC firstly increased and then decreased with the decrease of the molar ratio of Fe2+ to H2O2, while continuously increased with the increase of iron scraps and Fenton reaction time. Hydrogen Peroxide 151-155 acyl-CoA oxidase 1 Homo sapiens 46-49 33133786-2 2017 In this work, BuOH was first oxidized to n-butyraldehyde (BA) by the alcohol oxidase enzyme (AOx), concurrently generating hydrogen peroxide (H2O2). Hydrogen Peroxide 123-140 acyl-CoA oxidase 1 Homo sapiens 69-91 33133786-2 2017 In this work, BuOH was first oxidized to n-butyraldehyde (BA) by the alcohol oxidase enzyme (AOx), concurrently generating hydrogen peroxide (H2O2). Hydrogen Peroxide 123-140 acyl-CoA oxidase 1 Homo sapiens 93-96 33133786-2 2017 In this work, BuOH was first oxidized to n-butyraldehyde (BA) by the alcohol oxidase enzyme (AOx), concurrently generating hydrogen peroxide (H2O2). Hydrogen Peroxide 142-146 acyl-CoA oxidase 1 Homo sapiens 93-96 29055193-4 2018 The analytical system is based on the oxidation of cysteine (CSH) with hydrogen peroxide (H2O2) enzymatically generated by alcohol oxidase (AOx). Hydrogen Peroxide 71-88 acyl-CoA oxidase 1 Homo sapiens 123-138 29055193-4 2018 The analytical system is based on the oxidation of cysteine (CSH) with hydrogen peroxide (H2O2) enzymatically generated by alcohol oxidase (AOx). Hydrogen Peroxide 71-88 acyl-CoA oxidase 1 Homo sapiens 140-143 29055193-4 2018 The analytical system is based on the oxidation of cysteine (CSH) with hydrogen peroxide (H2O2) enzymatically generated by alcohol oxidase (AOx). Hydrogen Peroxide 90-94 acyl-CoA oxidase 1 Homo sapiens 123-138 29055193-4 2018 The analytical system is based on the oxidation of cysteine (CSH) with hydrogen peroxide (H2O2) enzymatically generated by alcohol oxidase (AOx). Hydrogen Peroxide 90-94 acyl-CoA oxidase 1 Homo sapiens 140-143 27830987-4 2016 Since AOX indirectly, is able to control the synthesis of important signaling molecules like hydrogen peroxide, superoxide, nitric oxide, thus it is also helping in stress signaling. Hydrogen Peroxide 93-110 acyl-CoA oxidase 1 Homo sapiens 6-9 29964470-4 2016 The optimal condition was determined as Fe2+:H2O2 ratio of 1:8, iron scraps reaction time of 4 h and Fenton reaction time of 60 min, under which 94.2% of AOX, 93.7% of chroma and 27.2% of TOC were removed. Hydrogen Peroxide 45-49 acyl-CoA oxidase 1 Homo sapiens 154-157 23328407-8 2013 These exhibit an imbalance between preserved hydrogen peroxide (H 2O 2)-generating acyl-CoA oxidase (ACOX) and dysfunctional/inactivated catalase (CAT), which leads to intra-peroxisomal redox disequilibrium. Hydrogen Peroxide 45-62 acyl-CoA oxidase 1 Homo sapiens 101-105 27115846-4 2016 The optimal pH, Fe(2+) concentration, molar ratio of H2O2/Fe(2+) and reaction time were found to be 3.3, 19.05 mM, 20.16 and 2.2 h, respectively, and 91.78% AOX and 75.01% TOC were removed under these conditions, which was validated. Hydrogen Peroxide 53-57 acyl-CoA oxidase 1 Homo sapiens 157-160 25612313-6 2015 The transduction mechanism for the biosensor was based on AOx-catalyzed oxidation of methanol to produce hydrogen peroxide. Hydrogen Peroxide 105-122 acyl-CoA oxidase 1 Homo sapiens 58-61 25495913-4 2015 With the mimicking sandwich-type reaction, the cascade catalysis amplification strategy was carried out by AOx catalyzing ethanol to acetaldehyde with the concomitant formation of high concentration of H2O2, which was further electrocatalyzed by PtNPs and Cyt c. Hydrogen Peroxide 202-206 acyl-CoA oxidase 1 Homo sapiens 107-110 24635054-5 2014 The leaves of nonstressed AOX knockdowns maintained concentrations of H2O2 and nitric oxide (NO) normally seen in wildtype plants only under stress conditions. Hydrogen Peroxide 70-74 acyl-CoA oxidase 1 Homo sapiens 26-29 23328407-8 2013 These exhibit an imbalance between preserved hydrogen peroxide (H 2O 2)-generating acyl-CoA oxidase (ACOX) and dysfunctional/inactivated catalase (CAT), which leads to intra-peroxisomal redox disequilibrium. Hydrogen Peroxide 64-70 acyl-CoA oxidase 1 Homo sapiens 101-105 22435679-13 2012 The decreased expressions of PPAR-alpha, carnitine palmitoyl transferase 1 (CPT1) and acyl-CoA oxidase (ACOX) induced by H2O2 can be attenuated by L-carnitine. Hydrogen Peroxide 121-125 acyl-CoA oxidase 1 Homo sapiens 86-102 22435679-13 2012 The decreased expressions of PPAR-alpha, carnitine palmitoyl transferase 1 (CPT1) and acyl-CoA oxidase (ACOX) induced by H2O2 can be attenuated by L-carnitine. Hydrogen Peroxide 121-125 acyl-CoA oxidase 1 Homo sapiens 104-108 22429403-10 2012 In addition, the inhibition of the AOX pathway increased the accumulation of hydrogen peroxide (H2O2), suggesting that the AOX pathway functions as an antioxidant mechanism. Hydrogen Peroxide 77-94 acyl-CoA oxidase 1 Homo sapiens 35-38 22429403-10 2012 In addition, the inhibition of the AOX pathway increased the accumulation of hydrogen peroxide (H2O2), suggesting that the AOX pathway functions as an antioxidant mechanism. Hydrogen Peroxide 77-94 acyl-CoA oxidase 1 Homo sapiens 123-126 22429403-10 2012 In addition, the inhibition of the AOX pathway increased the accumulation of hydrogen peroxide (H2O2), suggesting that the AOX pathway functions as an antioxidant mechanism. Hydrogen Peroxide 96-100 acyl-CoA oxidase 1 Homo sapiens 35-38 22429403-10 2012 In addition, the inhibition of the AOX pathway increased the accumulation of hydrogen peroxide (H2O2), suggesting that the AOX pathway functions as an antioxidant mechanism. Hydrogen Peroxide 96-100 acyl-CoA oxidase 1 Homo sapiens 123-126 22177543-5 2012 The hydrogel-entrapped GOX and AOX were able to perform enzyme-catalyzed oxidation of glucose and alcohol, respectively, to produce H(2)O(2), which subsequently quenched the fluorescence of the conjugated QDs. Hydrogen Peroxide 132-140 acyl-CoA oxidase 1 Homo sapiens 31-34