PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26019688-14	2015	In addition, ICAD overexpression also suppressed H2O2-induced MLL gene cleavage, suggesting a possible role of CAD in initiating chromosome cleavage during oxidative stress.	Hydrogen Peroxide	49-53	DNA fragmentation factor subunit beta	Homo sapiens	14-17	
30514321-16	2018	Furthermore, H2O2-induced cleavages within the SAR region were reduced by caspase-3 inhibitor, which indirectly inhibits CAD.	Hydrogen Peroxide	13-17	DNA fragmentation factor subunit beta	Homo sapiens	121-124	
27231526-16	2016	We further found that treatment with CI, which indirectly inhibits CAD, significantly reduced the chromosomal breaks in H2O2-cotreated cells.	Hydrogen Peroxide	120-124	DNA fragmentation factor subunit beta	Homo sapiens	67-70	
26019688-15	2015	CONCLUSIONS: Oxidative stress mediated by H2O2 induces cleavage of the MLL gene, most likely via the caspase-activated DNase, CAD, and CAD expression requires ICAD.	Hydrogen Peroxide	42-46	DNA fragmentation factor subunit beta	Homo sapiens	101-124	
26019688-15	2015	CONCLUSIONS: Oxidative stress mediated by H2O2 induces cleavage of the MLL gene, most likely via the caspase-activated DNase, CAD, and CAD expression requires ICAD.	Hydrogen Peroxide	42-46	DNA fragmentation factor subunit beta	Homo sapiens	126-129	
26019688-15	2015	CONCLUSIONS: Oxidative stress mediated by H2O2 induces cleavage of the MLL gene, most likely via the caspase-activated DNase, CAD, and CAD expression requires ICAD.	Hydrogen Peroxide	42-46	DNA fragmentation factor subunit beta	Homo sapiens	135-138