PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30668351-10	2019	The herbal drug-mediated transcriptional upregulation of human detoxifying UGT1A enzymes via activation of AhR and Nrf2 leads to reduced hydrogen peroxide and oxidative stress.	Hydrogen Peroxide	137-154	aryl hydrocarbon receptor	Homo sapiens	107-110	
28972393-7	2017	Knockdown of AhR attenuated the aforementioned effects caused by H2O2-induced oxidative stress.	Hydrogen Peroxide	65-69	aryl hydrocarbon receptor	Homo sapiens	13-16	
22415306-0	2012	Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 2: Epidermal H2O2/ONOO(-)-mediated stress in vitiligo hampers indoleamine 2,3-dioxygenase and aryl hydrocarbon receptor-mediated immune response signaling.	Hydrogen Peroxide	136-140	aryl hydrocarbon receptor	Homo sapiens	217-242	
26535918-11	2015	Together, the results suggest that SH-reactive agents via a new and possibly general NOX/H2O2-dependent mechanism can interfere with the endogenous regulation of the AHR.	Hydrogen Peroxide	89-93	aryl hydrocarbon receptor	Homo sapiens	166-169	
22392998-6	2012	The oxidants UVB irradiation and hydrogen peroxide and the model AHR antagonist 3"-methoxy-4"-nitroflavone all inhibited induction of CYP1A1 enzyme activity by FICZ or 2,3,7,8-tetrachlorodibenzo-p-dioxin, thereby subsequently elevating intracellular levels of FICZ and activating AHR.	Hydrogen Peroxide	33-50	aryl hydrocarbon receptor	Homo sapiens	280-283	
34847078-4	2022	Anakinra promoted H2O2-driven autophagy through a xenobiotic sensing pathway involving the aryl hydrocarbon receptor that, activated through the indoleamine 2,3-dioxygenase 1-kynurenine pathway, transcriptionally activates NADPH Oxidase 4 independent of the IL-1R1.	Hydrogen Peroxide	18-22	aryl hydrocarbon receptor	Homo sapiens	91-116