PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28558965-3	2017	The two electrons liberated are then passed to molecular oxygen by the renalase FAD cofactor forming hydrogen peroxide.	Hydrogen Peroxide	101-118	renalase, FAD dependent amine oxidase	Homo sapiens	71-79	
33338501-11	2021	After that, Caco-2 cell was treated with 2 mM H2O2 for 30 min or 24 h. KEY FINDINGS: Renalase was increased in Fast and it was localized in crypt.	Hydrogen Peroxide	46-50	renalase, FAD dependent amine oxidase	Homo sapiens	85-93	
33338501-13	2021	Renalase overexpression protects the Caco-2 cells against H2O2 induced oxidative stress.	Hydrogen Peroxide	58-62	renalase, FAD dependent amine oxidase	Homo sapiens	0-8	
33338501-16	2021	Actually, renalase protected Caco-2 cells against H2O2 induced oxidative stress.	Hydrogen Peroxide	50-54	renalase, FAD dependent amine oxidase	Homo sapiens	10-18	
27867452-6	2016	We observed a significant increase of renalase expression in HepG2 cells in a time- and dose-dependent manner when treated with H2O2.	Hydrogen Peroxide	128-132	renalase, FAD dependent amine oxidase	Homo sapiens	38-46	
17385068-5	2007	The claim of catecholamine-metabolising activity of renalase was based on the generation of H(2)O(2) during incubation of the enzyme with catecholamines.	Hydrogen Peroxide	92-100	renalase, FAD dependent amine oxidase	Homo sapiens	52-60	
26049000-4	2015	The reaction catalyzed defines renalase as an oxidase, one that harvests two electrons from either 2-dihydroNAD(P) or 6-dihydroNAD(P) to form beta-NAD(P)(+) and hydrogen peroxide.	Hydrogen Peroxide	161-178	renalase, FAD dependent amine oxidase	Homo sapiens	31-39	
24511138-4	2014	In this study, recombinant renalase protected human proximal tubular (HK-2) cells against cisplatin- and hydrogen peroxide-induced necrosis.	Hydrogen Peroxide	105-122	renalase, FAD dependent amine oxidase	Homo sapiens	27-35	
26016690-6	2015	Renalase serves to rapidly oxidize these isomers to form beta-NAD(P)+ and then pass the electrons to dioxygen, forming H2O2.	Hydrogen Peroxide	119-123	renalase, FAD dependent amine oxidase	Homo sapiens	0-8	
24266457-13	2013	Together these data suggest that the products are formed and released in a kinetically ordered sequence (beta-NADP+ then H2O2), however, the reoxidation of renalase is not contingent on the dissociation of beta-NADP+.	Hydrogen Peroxide	121-125	renalase, FAD dependent amine oxidase	Homo sapiens	156-164