PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3355526-7 1988 H2O2, TBH and CH, each with Cu2+, gave rise to substantial fragmentation of the protein bovine serum albumin (BSA). Hydrogen Peroxide 0-4 albumin Homo sapiens 95-108 33216850-0 2020 2",7"-dichlorofluorescin-based analysis of Fenton chemistry reveals auto-amplification of probe fluorescence and albumin as catalyst for the detection of hydrogen peroxide. Hydrogen Peroxide 154-171 albumin Homo sapiens 113-120 6329953-3 1984 Light emission from a cell-free MPO-H2O2 system was found to be totally inhibited by human serum albumin (HSA), and since HSA is a large molecular protein that does not readily gain access to intracellular sites of PMNL, it could be used to determine the importance of extra- and intracellular events in PMNL chemiluminescence. Hydrogen Peroxide 36-40 albumin Homo sapiens 91-104 33216850-6 2020 Surprisingly, the addition of bovine serum albumin rendered DCF sensitive to H2O2 as well. Hydrogen Peroxide 77-81 albumin Homo sapiens 37-50 32537936-3 2020 Here, the prodrug tirapazamine (TPZ)-loaded human serum albumin (HSA)-glucose oxidase (GOx) mixture is prepared and modified with a metal-polyphenol network composed of ferric ions (Fe3+ ) and tannic acid (TA), to obtain a self-amplified nanoreactor termed HSA-GOx-TPZ-Fe3+ -TA (HGTFT) for sustainable and cascade cancer therapy with exogenous H2 O2 production and TA-accelerated Fe3+ /Fe2+ conversion. Hydrogen Peroxide 344-349 albumin Homo sapiens 50-85 32824562-7 2020 Moreover, in HL-1 cardiomyocytes incubated with H2O2, we showed a significant decrease of cell viability in cells treated with thio-HSA in respect to restored native-HSA. Hydrogen Peroxide 48-52 albumin Homo sapiens 132-135 32824562-7 2020 Moreover, in HL-1 cardiomyocytes incubated with H2O2, we showed a significant decrease of cell viability in cells treated with thio-HSA in respect to restored native-HSA. Hydrogen Peroxide 48-52 albumin Homo sapiens 166-169 32605272-9 2020 Furthermore, the PMs protect the Cur against the photo-degradation, whereas the non-ionic PEO corona limits the adsorption of bovine serum albumin (BSA) protein on the surface. Hydrogen Peroxide 90-93 albumin Homo sapiens 133-146 32469044-1 2020 An artificial protein-probe hybrid, Cm-Np-B@BSA, was prepared via host-guest interactions between hydrogen peroxide (H2O2)-responsive Cm-Np-B molecule and bovine serum albumin (BSA). Hydrogen Peroxide 98-115 albumin Homo sapiens 162-175 32469044-1 2020 An artificial protein-probe hybrid, Cm-Np-B@BSA, was prepared via host-guest interactions between hydrogen peroxide (H2O2)-responsive Cm-Np-B molecule and bovine serum albumin (BSA). Hydrogen Peroxide 117-121 albumin Homo sapiens 162-175 27790352-3 2016 METHODS: In this 2015 experiment, different ratios of Fenton reagent (Fe2+/H2O2) was incubated with one concentration of human serum albumin (1mg/ml). Hydrogen Peroxide 75-79 albumin Homo sapiens 127-140 31270687-10 2019 Graphical abstract The catalytic activity of porous-hollow nano-UO2 toward the oxidation of 3,3",5,5"-tetramethylbenzidine by H2O2 is remarkably improved in the presence of bovine serum albumin, while tin(II) inhibits its activity. Hydrogen Peroxide 126-130 albumin Homo sapiens 180-193 30953845-2 2019 Here, we developed a novel H2O2-activatable and biodegradable nanomedicine (BSA-MBPB) by encapsulation of a single newly synthesized pro-photosensitizer (MBPB) with its photoactivity completely annihilated within bovine serum albumin (BSA) to achieve imaging-guided tumor-targeted effective PDT. Hydrogen Peroxide 27-31 albumin Homo sapiens 220-233 30324533-5 2019 Therefore, we proposed that studying the protection mechanism of SA against the heme/H2O2/NO2--induced cytotoxicity may be more consistent with free heme-associated disorder pathologies. Hydrogen Peroxide 85-89 albumin Homo sapiens 65-67 29525695-5 2018 Our results showed that FeTPPS induced bovine serum albumin (BSA) nitration in the presence of H2O2 and NaNO2, and the reaction was dose-, time- and pH-dependent. Hydrogen Peroxide 95-99 albumin Homo sapiens 46-59 29432786-9 2018 Oxidative stress applied by addition of H2O2 revealed induction of ApoO transcript and protein level in the same or even higher extent as monitored in the presence of OA-Alb. Hydrogen Peroxide 40-44 albumin Homo sapiens 170-173 28728113-1 2017 A new amperometric hydrogen peroxide enzyme inhibition biosensor for the indirect determination of toxic mercury ions, Hg2+, based on catalase immobilized on a glassy carbon electrode surface by cross-linking with glutaraldehyde and bovine serum albumin, is reported. Hydrogen Peroxide 19-36 albumin Homo sapiens 240-253 27062681-5 2016 Furthermore, we found using chemiluminescent analysis that the antioxidant capacities for N-ALB to scavenge reactive oxygen species including singlet oxygen, hypochlorite and hydrogen peroxide were higher than HD-ALB. Hydrogen Peroxide 175-192 albumin Homo sapiens 92-95 32879229-5 2020 Human serum albumin complexed with hemin was labeled at Tyr138, the tyrosine residue closest to the hemin binding site and most strongly subjected to oxidative stress caused by hemin/H2O2. Hydrogen Peroxide 183-187 albumin Homo sapiens 6-19 29278949-4 2018 The results presented herein show that highly concentrated solutions of bovine serum albumin (BSA) exposed to peroxynitrite, or metmyoglobin/H2O2, initiate the formation and propagation of protein peroxyl radicals, as evidenced by oxygen consumption, fluorescence spectroscopy, chemiluminescence, and electron paramagnetic resonance studies. Hydrogen Peroxide 141-145 albumin Homo sapiens 79-92 28438657-2 2017 Three experimental approaches (pH-dependence of reactivity towards hydrogen peroxide, ultraviolet titration and infrared spectroscopy) are used to determine that the pKa value in delipidated HSA is 8.1+-0.2 at 37 C and 0.1M ionic strength. Hydrogen Peroxide 67-84 albumin Homo sapiens 191-194 28438657-11 2017 These studies contribute to deepen the understanding of the reactivity of HSA-SH, the most abundant thiol in human plasma, and in a wider perspective, provide clues on the key aspects that modulate thiol reactivity against H2O2. Hydrogen Peroxide 223-227 albumin Homo sapiens 74-77 24416244-5 2014 In this work, we investigated the effect of hydrogen peroxide oxidation on Human Serum Albumin (HSA) structure, thermal stability and aggregation properties. Hydrogen Peroxide 44-61 albumin Homo sapiens 81-94 27075699-0 2016 Bovine serum albumin-cobalt(ii) Schiff base complex hybrid: an efficient artificial metalloenzyme for enantioselective sulfoxidation using hydrogen peroxide. Hydrogen Peroxide 139-156 albumin Homo sapiens 7-20 26592577-2 2016 In this CRET platform, bis(2,4,6-trichlorophenyl)oxalate-hydrogen peroxide chemiluminescence (CL) reaction was utilized as an energy donor and bovine serum albumin (BSA)-stabilized gold nanoclusters (Au NCs) as an energy acceptor. Hydrogen Peroxide 57-74 albumin Homo sapiens 150-163 25038538-1 2014 Platinum nanoparticles (PtNPs) in the scaffold of bovine serum albumin (BSA) through biomineralization are found to possess excellent peroxidase-like activity that can catalyze N-ethyl-N-(3-sulfopropyl)-3-methylaniline sodium salt (TOPS) coupled with 4-amino-antipyrine (4-AAP) by the action of hydrogen peroxide to give an obvious purple product. Hydrogen Peroxide 295-312 albumin Homo sapiens 57-70 22645466-0 2012 Effect of human and bovine serum albumin on kinetic chemiluminescence of Mn (III)-Tetrakis (4-sulfonatophenyl) porphyrin-luminol-hydrogen peroxide system. Hydrogen Peroxide 129-146 albumin Homo sapiens 27-40 23624303-9 2013 When heme and hydrogen peroxide were added to human plasma, heme was found to oxidize proteins, primarily and predominantly HSA; however, when HSA-depleted plasma was used, heme triggered the oxidation of several other proteins, including transferrin. Hydrogen Peroxide 14-31 albumin Homo sapiens 124-127 23624303-10 2013 Thus, HSA in plasma protected other proteins from heme/H2O2-induced oxidation. Hydrogen Peroxide 55-59 albumin Homo sapiens 6-9 23938445-1 2013 A gold nanocluster@bovine serum albumin-silica nanoparticle composite has been synthesized and used for the solid-state electrochemiluminescence (ECL) sensing of hydrogen peroxide. Hydrogen Peroxide 162-179 albumin Homo sapiens 26-39 22645466-1 2012 The present work deals with an attempt to study the effect of human and bovine serum albumin on kinetic parameters of chemiluminescence of luminol-hydrogen peroxide system catalyzed by manganese tetrasulfonatophenyl porphyrin (MnTSPP). Hydrogen Peroxide 147-164 albumin Homo sapiens 79-92 19939642-3 2010 We have determined that the sensitivity of the biosensor design, defined as its response to the reducing agent hydrogen peroxide, is highly dependent on the presence of bovine serum albumin (BSA) and less dependent on the presence of the enzyme glucose oxidase. Hydrogen Peroxide 111-128 albumin Homo sapiens 176-189 17477045-1 2007 Changes in the fluorescence of beta-carotene and chlorophyll a and their mixtures in different molar ratios under the action of hydrogen peroxide have been registered in two cases: (1) in Langmuir films and (2) in a complex with bovine serum albumin in water solution. Hydrogen Peroxide 128-145 albumin Homo sapiens 236-249 18459802-0 2008 Completely different effects of desferrioxamine on hemin/nitrite/H2O2-induced bovine serum albumin nitration and oxidation. Hydrogen Peroxide 65-69 albumin Homo sapiens 85-98 18459802-4 2008 In the hemin/nitrite/H2O2 system-induced bovine serum albumin (BSA) nitration and oxidation model, BSA was analyzed for 3-nitrotyosine and carbonyl groups measured by spectrophotometry, SDS-PAGE, and Western blotting upon exposure to DFO. Hydrogen Peroxide 21-25 albumin Homo sapiens 48-61 18363334-5 2008 Moreover the adsorption sites of AChE would not be blocked by bovine serum albumin (BSA) which provides a good platform for the quantitative amperometric determination of AChE via the oxidation of the enzymatically generated H 2O 2 in the bienzyme system in the presence of acetylcholine. Hydrogen Peroxide 225-231 albumin Homo sapiens 69-82 12240279-1 2001 Ion-exchange of [Ti,Al]-beta with quaternary ammonium acetates greatly enhances the epoxide selectivity in the oxidation of alkenes with hydrogen peroxide; this is due to the selective poisoning of the acid sites without suppressing the oxidation activity of Ti sites. Hydrogen Peroxide 137-154 albumin Homo sapiens 20-28 12924939-0 2003 Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite. Hydrogen Peroxide 50-67 albumin Homo sapiens 33-46 11687295-1 2001 Incubation of human hemoglobin with nitrite and hydrogen peroxide was found to induce autonitration and nitration of another protein (bovine serum albumin), as demonstrated by detection of nitrotyrosine residues in Western blots of separated membrane proteins. Hydrogen Peroxide 48-65 albumin Homo sapiens 141-154 14717588-4 2004 Here, we used EPR methodologies to study bovine serum albumin (BSA) oxidation by Cu,Zn-SOD/hydrogen peroxide in the absence and presence of bicarbonate or nitrite. Hydrogen Peroxide 91-108 albumin Homo sapiens 48-61 12849078-1 2003 On exposure to free radicals generated by the Fenton reaction system of Fe(2+)/EDTA/H(2)O(2)/ascorbate, bovine serum albumin (BSA), used as a model of water-soluble protein, was losing its water solubility depending on the concentration of the chelated iron. Hydrogen Peroxide 84-92 albumin Homo sapiens 111-124 11811527-0 2001 Protein radicals in the reaction between H2O2-activated metmyoglobin and bovine serum albumin. Hydrogen Peroxide 41-45 albumin Homo sapiens 80-93 9473299-0 1998 Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin. Hydrogen Peroxide 8-22 albumin Homo sapiens 100-113 11465418-1 2001 PURPOSE: Human serum albumin (HSA) was mildly oxidized by a metal-catalyzed oxidation system (MCO-HSA), chloramine-T (CT-HSA) or H2O2 (H2O2-HSA), and the effects of these treatments on the structural, drug-binding and esterase-like properties were studied. Hydrogen Peroxide 129-133 albumin Homo sapiens 15-28 10443938-4 1999 The heme complexes with Hx or Alb (1:1 = protein:heme) therefore had a much lower reactivity toward H2O2 and Cum-OOH than the nonprotein heme. Hydrogen Peroxide 100-104 albumin Homo sapiens 30-33 10443938-5 1999 A kinetic analysis suggested that binding to Hx or Alb inhibited the primary activation of heme by H2O2, the step common for both peroxidase- and catalaselike activities of hemin. Hydrogen Peroxide 99-103 albumin Homo sapiens 51-54 11410286-5 2001 In spite of these limitations, the hemin-HSA complex promotes hydrogen peroxide activation processes that bear the characteristics of enzymatic reactions and may have biological relevance. Hydrogen Peroxide 62-79 albumin Homo sapiens 41-44 8670254-7 1996 These results suggest that serum albumin acts as a major and predominate antioxidant exerting a glutathione-linked thiol peroxidase activity which removes reactive oxygen species such as H2O2 within blood plasma. Hydrogen Peroxide 187-191 albumin Homo sapiens 27-40 9296445-12 1997 The incubation of HSA with reducing agents such as uric acid or bilirubin in the presence of high Cu concentrations, produces a "peroxidase-like" activity, capable of breaking down hydrogen peroxide as well as lipid hydroperoxides. Hydrogen Peroxide 181-198 albumin Homo sapiens 18-21 8373198-0 1993 Mass spectrometric identification of modifications to human serum albumin treated with hydrogen peroxide. Hydrogen Peroxide 87-104 albumin Homo sapiens 60-73 7964173-4 1994 Production of H2O2 was observed when fMLP, TNF-alpha, or HAIgG was added to PMNs adherent to bovine serum albumin (BSA)-coated wells, but significant production of HOCl was observed only when HAIgG was added to PMNs adherent to BSA-coated wells or when suspended PMNs treated with TNF-alpha were allowed to settle in BSA-coated wells. Hydrogen Peroxide 14-18 albumin Homo sapiens 100-113 8373198-1 1993 Oxidized amino acid residues in human serum albumin exposed to hydrogen peroxide have been identified in tryptic peptides using liquid secondary ion mass spectrometry. Hydrogen Peroxide 63-80 albumin Homo sapiens 38-51 8391001-0 1993 Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin). Hydrogen Peroxide 42-59 albumin Homo sapiens 0-7 34794446-3 2021 RESULTS: In this study, we described a hydrogen peroxide (H2O2) responsive manganese dioxide mineralized albumin nanocomposite loading with mitochondria function inhibitor phenformin (PM) and near-infrared photothermal dye indocyanine green (ICG) by modified two-step biomineralization method. Hydrogen Peroxide 39-56 albumin Homo sapiens 105-112 34794446-3 2021 RESULTS: In this study, we described a hydrogen peroxide (H2O2) responsive manganese dioxide mineralized albumin nanocomposite loading with mitochondria function inhibitor phenformin (PM) and near-infrared photothermal dye indocyanine green (ICG) by modified two-step biomineralization method. Hydrogen Peroxide 58-62 albumin Homo sapiens 105-112