PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27462186-8	2016	Depletion of Top2beta increased the sensitivity of NCH421k cells to replication stress inducing drugs, such as cisplatin, methyl-methanesulfonate, hydrogen peroxide, and temozolomide.	Hydrogen Peroxide	147-164	DNA topoisomerase II beta	Homo sapiens	13-21	
18187655-4	2008	Localized demethylation produces hydrogen peroxide, which modifies the surrounding DNA and recruits 8-oxoguanine-DNA glycosylase 1 and topoisomeraseIIbeta, triggering chromatin and DNA conformational changes that are essential for estrogen-induced transcription.	Hydrogen Peroxide	33-50	DNA topoisomerase II beta	Homo sapiens	135-154