PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19539716-0	2009	Hydrogen peroxide induces autophagic cell death in C6 glioma cells via BNIP3-mediated suppression of the mTOR pathway.	Hydrogen Peroxide	0-17	BCL2 interacting protein 3	Homo sapiens	71-76	
19925863-7	2010	In addition, the increase in BNIP-3 levels induced by C3G knock-down in wt cells treated with H2O2 might play a role preventing cell death.	Hydrogen Peroxide	94-98	BCL2 interacting protein 3	Homo sapiens	29-35	
19539716-4	2009	The findings also show that H(2)O(2) induces the dephosphorylation of the mammalian target of rapamycin (mTOR) at Ser 2481 and the p70 ribosomal protein S6 kinase (p70S6K) at Thr389 in a Bcl-2/E1B 19kDa interacting protein 3 (BNIP3)-dependent manner.	Hydrogen Peroxide	28-36	BCL2 interacting protein 3	Homo sapiens	226-231	
19539716-6	2009	This suggests that BNIP3 may mediate H(2)O(2)-induced autophagic cell death through the suppression of mTOR.	Hydrogen Peroxide	37-45	BCL2 interacting protein 3	Homo sapiens	19-24	
19539716-7	2009	The findings show that the down-regulation of BNIP3 by BNIP3 siRNA prevents C6 cells from undergoing H(2)O(2)-induced autophagic cell death.	Hydrogen Peroxide	101-109	BCL2 interacting protein 3	Homo sapiens	46-51	
19539716-7	2009	The findings show that the down-regulation of BNIP3 by BNIP3 siRNA prevents C6 cells from undergoing H(2)O(2)-induced autophagic cell death.	Hydrogen Peroxide	101-109	BCL2 interacting protein 3	Homo sapiens	55-60	
19539716-8	2009	Collectively, these results suggest that H(2)O(2) induces autophagic cell death in C6 cells via the BNIP3-mediated suppression of the mTOR pathway.	Hydrogen Peroxide	41-49	BCL2 interacting protein 3	Homo sapiens	100-105	
32801360-6	2020	The increased H2O2 promotes silibinin-induced BNIP3 upregulation and translocation to mitochondria.	Hydrogen Peroxide	14-18	BCL2 interacting protein 3	Homo sapiens	46-51	
17397968-7	2007	Gene expression microarrays were employed to examine the specific transcriptional changes in N27 cells exposed to 100 microM H2O2 for 4 h. Changes in genes encoding pro- or anti-apoptotic proteins included up-regulation of BIK, PAWR, STAT5B, NPAS2, Jun B, MEK4, CCT7, PPP3CC, and PSDM3, while key down-regulated genes included BNIP3, NPTXR, RAGA, STK6, YWHAH, and MAP2K1.	Hydrogen Peroxide	125-129	BCL2 interacting protein 3	Homo sapiens	327-332	
30147831-10	2018	In EEP-induced cardioprotection, EEP provided suppression to exhaustive exercise (EE) injuries by translocating Bnip3 to the mitochondria by recruiting the autophagosome protein LC3 to induce mitophagy, which is potentially triggered by H2O2 and influenced by Beclin1-dependent autophagy.	Hydrogen Peroxide	237-241	BCL2 interacting protein 3	Homo sapiens	112-117	
32190178-0	2020	MicroRNA-103 Protects Coronary Artery Endothelial Cells against H2O2-Induced Oxidative Stress via BNIP3-Mediated End-Stage Autophagy and Antipyroptosis Pathways.	Hydrogen Peroxide	64-68	BCL2 interacting protein 3	Homo sapiens	98-103