PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32063362-4	2020	Human lens epithelial cells expressing AQP1, AQP5 and AQP8, when treated with 50 muM HgCl2 water channel inhibitor showed a significant reduction in H2O2 transport.	Hydrogen Peroxide	149-153	aquaporin 1 (Colton blood group)	Homo sapiens	39-43	
34145535-6	2021	mRNA expression (aquaporin-1 and aquaporin-3) and hyaluronan secretion associated with skin moisturization were reduced by H2O2 treatment, whereas MSC-Ex reversed these effects.	Hydrogen Peroxide	123-127	aquaporin 1 (Colton blood group)	Homo sapiens	17-28	
33028705-0	2020	Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide.	Hydrogen Peroxide	100-117	aquaporin 1 (Colton blood group)	Homo sapiens	14-25	
30175205-3	2018	In addition, the obtained data suggest an association between the gene expression levels of AQP (1, 3, 8, and 9) and the difference in hydrogen peroxide (H2O2) sensitivity between rho0 and CRR cells.	Hydrogen Peroxide	135-152	aquaporin 1 (Colton blood group)	Homo sapiens	92-111	
31521632-7	2020	Overall, we conclude that AtPIP2;4, SoPIP2;1 and hAQP1 are all transporters of both H2O and H2O2, but have different efficiencies for various specificities.	Hydrogen Peroxide	92-96	aquaporin 1 (Colton blood group)	Homo sapiens	49-54	
31364739-10	2019	In addition, epithelial-mesenchymal transition occurred upon ROS accumulation, whereas the effects of H2O2 on AQP1 and vimentin expression were reversed upon LC supplementation.	Hydrogen Peroxide	102-106	aquaporin 1 (Colton blood group)	Homo sapiens	110-114	
31316715-4	2019	We apply molecular dynamics simulations to investigate the permeation of both hydrophilic (H2O2 and OH) and hydrophobic (NO2 and NO) RONS through AQP1.	Hydrogen Peroxide	91-95	aquaporin 1 (Colton blood group)	Homo sapiens	146-150	
31316715-6	2019	The permeation free energy barrier of OH and NO is lower than that of H2O2 and NO2, indicating that these radicals may have easier access to the pore interior and interact with the amino acid residues of AQP1.	Hydrogen Peroxide	70-74	aquaporin 1 (Colton blood group)	Homo sapiens	204-208	
30175205-3	2018	In addition, the obtained data suggest an association between the gene expression levels of AQP (1, 3, 8, and 9) and the difference in hydrogen peroxide (H2O2) sensitivity between rho0 and CRR cells.	Hydrogen Peroxide	154-158	aquaporin 1 (Colton blood group)	Homo sapiens	92-111	
24286224-7	2014	Differences from an earlier report showing an absence of H2O2 permeability of human AQP1 can be explained by expression levels.	Hydrogen Peroxide	57-61	aquaporin 1 (Colton blood group)	Homo sapiens	84-88	
22997161-5	2013	We hypothesized that extracellular H(2)O(2) induces smooth muscle cell (SMC) hypertrophy by a mechanism involving Aqp1, Nox1, and Ask1.	Hydrogen Peroxide	35-43	aquaporin 1 (Colton blood group)	Homo sapiens	114-118	
22997161-8	2013	Aqp1 siRNA attenuated H(2)O(2) cellular entry and H(2)O(2)-induced O(2)( -) production.	Hydrogen Peroxide	22-30	aquaporin 1 (Colton blood group)	Homo sapiens	0-4	
22997161-8	2013	Aqp1 siRNA attenuated H(2)O(2) cellular entry and H(2)O(2)-induced O(2)( -) production.	Hydrogen Peroxide	50-58	aquaporin 1 (Colton blood group)	Homo sapiens	0-4	
19424603-4	2009	Ultraviolet radiation (UVB) and H2O2, two major factors causing RPE cell damage, induced AQP1 downregulation which was mediated by MEK/ERK activation.	Hydrogen Peroxide	32-36	aquaporin 1 (Colton blood group)	Homo sapiens	89-93	
19424603-6	2009	Notably, pretreatment with all-trans retinoic acid attenuated UV- and H2O2-induced AQP1 downregulation and water permeability impairment.	Hydrogen Peroxide	70-74	aquaporin 1 (Colton blood group)	Homo sapiens	83-87