PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29909290-3	2018	REDD1 protein was increased in H2O2 or tert-butylhydroperoxide (t-BHP)-treated hepatocytes  H2O2 also elevated REDD1 mRNA levels.	Hydrogen Peroxide	31-35	DNA damage inducible transcript 4	Homo sapiens	0-5	
23660824-0	2013	Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation.	Hydrogen Peroxide	29-46	DNA damage inducible transcript 4	Homo sapiens	94-99	
23660824-11	2013	These findings suggested that salidroside was capable of protecting HUVECs against H2O2-induced apoptosis by activating the PI3K/Akt/mTOR-dependent pathway and inhibiting ROS production by activating REDD1.	Hydrogen Peroxide	83-87	DNA damage inducible transcript 4	Homo sapiens	200-205	
34603601-7	2021	Importantly, REDD1 formed a complex with TXNIP to strengthen its own action, and the combination was consolidated under H2O2-induced oxidative stress.	Hydrogen Peroxide	120-124	DNA damage inducible transcript 4	Homo sapiens	13-18	
34603601-10	2021	Altogether, our results demonstrated that the REDD1/TXNIP complex mediated H2O2-induced human NP cell apoptosis and IVD degeneration through the mitochondrial pathway.	Hydrogen Peroxide	75-79	DNA damage inducible transcript 4	Homo sapiens	46-51	
29909290-3	2018	REDD1 protein was increased in H2O2 or tert-butylhydroperoxide (t-BHP)-treated hepatocytes  H2O2 also elevated REDD1 mRNA levels.	Hydrogen Peroxide	31-35	DNA damage inducible transcript 4	Homo sapiens	111-116	
29909290-3	2018	REDD1 protein was increased in H2O2 or tert-butylhydroperoxide (t-BHP)-treated hepatocytes  H2O2 also elevated REDD1 mRNA levels.	Hydrogen Peroxide	92-96	DNA damage inducible transcript 4	Homo sapiens	0-5	
29909290-3	2018	REDD1 protein was increased in H2O2 or tert-butylhydroperoxide (t-BHP)-treated hepatocytes  H2O2 also elevated REDD1 mRNA levels.	Hydrogen Peroxide	92-96	DNA damage inducible transcript 4	Homo sapiens	111-116	
29909290-5	2018	Interestingly, we found that H2O2-mediated REDD1 induction was transcriptionally regulated by activator protein-1 (AP-1), and that overexpression of c-Jun increased REDD1 protein levels and REDD1 promoter-driven luciferase activity.	Hydrogen Peroxide	29-33	DNA damage inducible transcript 4	Homo sapiens	43-48	
29909290-5	2018	Interestingly, we found that H2O2-mediated REDD1 induction was transcriptionally regulated by activator protein-1 (AP-1), and that overexpression of c-Jun increased REDD1 protein levels and REDD1 promoter-driven luciferase activity.	Hydrogen Peroxide	29-33	DNA damage inducible transcript 4	Homo sapiens	165-170	
29909290-5	2018	Interestingly, we found that H2O2-mediated REDD1 induction was transcriptionally regulated by activator protein-1 (AP-1), and that overexpression of c-Jun increased REDD1 protein levels and REDD1 promoter-driven luciferase activity.	Hydrogen Peroxide	29-33	DNA damage inducible transcript 4	Homo sapiens	165-170	
29909290-8	2018	Furthermore, we observed that REDD1 overexpression attenuated H2O2 or t-BHP-derived reactive oxygen species formation as well as cytotoxicity.	Hydrogen Peroxide	62-66	DNA damage inducible transcript 4	Homo sapiens	30-35