PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32739156-5 2020 Intracellular H4R3me2s was significantly increased after treatment with the DNA oxidant reagent H2O2, and this increase was regulated by OGG1, which could directly interact with the specific arginine methyltransferase, PRMT5. Hydrogen Peroxide 96-100 protein arginine methyltransferase 5 Homo sapiens 219-224 26972221-9 2016 PRMT5 expression was down-regulated in senescent and H2O2-treated macrophages rendering ineffectual induction of MHC II transcription by IFN-gamma. Hydrogen Peroxide 53-57 protein arginine methyltransferase 5 Homo sapiens 0-5 26912789-4 2016 Moreover, PRMT5-mediated ASK1 methylation impaired the H2O2-induced activity of ASK1, and this inhibitory effect of PRMT5 was abolished by replacement of arginine 89 with Trp or depletion of PRMT5 expression by RNA interference. Hydrogen Peroxide 55-59 protein arginine methyltransferase 5 Homo sapiens 10-15 26912789-4 2016 Moreover, PRMT5-mediated ASK1 methylation impaired the H2O2-induced activity of ASK1, and this inhibitory effect of PRMT5 was abolished by replacement of arginine 89 with Trp or depletion of PRMT5 expression by RNA interference. Hydrogen Peroxide 55-59 protein arginine methyltransferase 5 Homo sapiens 116-121 26912789-4 2016 Moreover, PRMT5-mediated ASK1 methylation impaired the H2O2-induced activity of ASK1, and this inhibitory effect of PRMT5 was abolished by replacement of arginine 89 with Trp or depletion of PRMT5 expression by RNA interference. Hydrogen Peroxide 55-59 protein arginine methyltransferase 5 Homo sapiens 116-121