PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34052344-9 2021 H2O2 induced cellular injury and inflammation, excessive ROS production, mitochondrial abnormalities, and increased expression of p-Drp1 and Drp1 in hPDLCs, which could be reversed by NAC and Mdivi-1. Hydrogen Peroxide 0-4 dynamin 1 like Homo sapiens 132-136 34052344-9 2021 H2O2 induced cellular injury and inflammation, excessive ROS production, mitochondrial abnormalities, and increased expression of p-Drp1 and Drp1 in hPDLCs, which could be reversed by NAC and Mdivi-1. Hydrogen Peroxide 0-4 dynamin 1 like Homo sapiens 141-145 25008790-0 2014 Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting. Hydrogen Peroxide 34-51 dynamin 1 like Homo sapiens 75-79 30347228-10 2018 The H2O2-treated EH cells showed diminished Gli1 and increased Drp1 expression, concurrent with reduced p-Drp1-(serine637). Hydrogen Peroxide 4-8 dynamin 1 like Homo sapiens 63-67 30347228-10 2018 The H2O2-treated EH cells showed diminished Gli1 and increased Drp1 expression, concurrent with reduced p-Drp1-(serine637). Hydrogen Peroxide 4-8 dynamin 1 like Homo sapiens 106-110 29110115-6 2018 Mutation of DNM1L was also associated with impaired responses to oxidative stress, as treatment with hydrogen peroxide dramatically increased cellular ROS, with minimal exacerbation of already impaired mitochondrial function. Hydrogen Peroxide 101-118 dynamin 1 like Homo sapiens 12-17 25008790-9 2014 H2O2 activates Drp1, resulting in its association with the mitochondria, mitochondrial fission and cell death in vitro and in vivo. Hydrogen Peroxide 0-4 dynamin 1 like Homo sapiens 15-19 24631294-5 2014 When myocytes were exposed to hydrogen peroxide (H2O2), they increased DRP1 expression and mitochondrial fragmentation, resulting in DeltaPsim depolarization and insulin resistance. Hydrogen Peroxide 49-53 dynamin 1 like Homo sapiens 71-75 24740540-7 2014 To investigate whether H2O2-induced fragmentation was mediated by dynamin-related protein 1, we incubated cells with mDivi1, an inhibitor of dynamin-related protein 1 translocation to mitochondria. Hydrogen Peroxide 23-27 dynamin 1 like Homo sapiens 66-91 24740540-7 2014 To investigate whether H2O2-induced fragmentation was mediated by dynamin-related protein 1, we incubated cells with mDivi1, an inhibitor of dynamin-related protein 1 translocation to mitochondria. Hydrogen Peroxide 23-27 dynamin 1 like Homo sapiens 141-166 24631294-6 2014 When DRP1 was suppressed by siRNA, H2O2-induced mitochondrial dysfunction and insulin resistance were restored. Hydrogen Peroxide 35-39 dynamin 1 like Homo sapiens 5-9 24631294-5 2014 When myocytes were exposed to hydrogen peroxide (H2O2), they increased DRP1 expression and mitochondrial fragmentation, resulting in DeltaPsim depolarization and insulin resistance. Hydrogen Peroxide 30-47 dynamin 1 like Homo sapiens 71-75