PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34158609-3	2021	The absence of GPx1 augmented TNF-alpha-induced apoptosis in various RIPK3-negative cancer cells by markedly elevating the level of cytosolic H2O2, which is derived from mitochondria.	Hydrogen Peroxide	142-146	receptor interacting serine/threonine kinase 3	Homo sapiens	69-74	
29608987-0	2018	RIP1 and RIP3 contribute to shikonin-induced glycolysis suppression in glioma cells via increase of intracellular hydrogen peroxide.	Hydrogen Peroxide	114-131	receptor interacting serine/threonine kinase 3	Homo sapiens	9-13	
29608987-7	2018	Notably, inhibition of RIP1 or RIP3 prevented intracellular H2O2 accumulation, which was correlated with preventing shikonin-induced downregulation of x-CT and depletion of GSH and cysteine.	Hydrogen Peroxide	60-64	receptor interacting serine/threonine kinase 3	Homo sapiens	31-35	
29608987-9	2018	Taken together, we demonstrated in this study that RIP1 and RIP3 contributed to shikonin-induced glycolysis suppression via increasing intracellular H2O2.	Hydrogen Peroxide	149-153	receptor interacting serine/threonine kinase 3	Homo sapiens	60-64	
27258785-5	2016	Our results show that RIPK1 and RIPK3 participate in H2O2-induced cardiomyocytes necrosis.	Hydrogen Peroxide	53-57	receptor interacting serine/threonine kinase 3	Homo sapiens	32-37