PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24553354-0	2014	Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells.	Hydrogen Peroxide	0-17	checkpoint kinase 2	Homo sapiens	22-26	
27174643-7	2016	Intriguingly, Ubc9 D100A cells fail to maintain activity of the ATM-Chk2 DNA damage response pathway that is induced by hydrogen peroxide.	Hydrogen Peroxide	120-137	checkpoint kinase 2	Homo sapiens	68-72	
28751929-6	2017	H2O2-induced activation of checkpoint kinase 2 (Chk2) was significantly attenuated after the preconditioning of BBR.	Hydrogen Peroxide	0-4	checkpoint kinase 2	Homo sapiens	27-46	
34144191-2	2021	When cells are exposed to exogenously added H2O2, ATR/CHK1 and ATM/CHK2 dependent DNA damage signaling is switched on, suggesting that H2O2 induces both single and double strand breaks.	Hydrogen Peroxide	44-48	checkpoint kinase 2	Homo sapiens	67-71	
34144191-2	2021	When cells are exposed to exogenously added H2O2, ATR/CHK1 and ATM/CHK2 dependent DNA damage signaling is switched on, suggesting that H2O2 induces both single and double strand breaks.	Hydrogen Peroxide	135-139	checkpoint kinase 2	Homo sapiens	67-71	
35436464-6	2022	Furthermore, mutated LCL displayed lower levels of phospho-Chk1 and phospho-Chk2 following hydrogen peroxide-induced oxidative stress, indicating a poorly effective DNA damage checkpoint, as well as reduced basal levels of p53.	Hydrogen Peroxide	91-108	checkpoint kinase 2	Homo sapiens	76-80	
22290195-6	2012	RESULTS: H(2) O(2) induced apoptosis and phosphorylation of ATM, Chk2, and H2AX in LNCaP cells.	Hydrogen Peroxide	9-18	checkpoint kinase 2	Homo sapiens	65-69	
34960710-5	2021	We determined that treatment of HBc-expressing hepatocytes with genotoxic agents, e.g., etoposide or hydrogen peroxide, activated the host ATM-Chk2 pathway, as determined by increased phosphorylation of ATM at Ser1981 and Chk2 at Thr68.	Hydrogen Peroxide	101-118	checkpoint kinase 2	Homo sapiens	143-147	
34960710-5	2021	We determined that treatment of HBc-expressing hepatocytes with genotoxic agents, e.g., etoposide or hydrogen peroxide, activated the host ATM-Chk2 pathway, as determined by increased phosphorylation of ATM at Ser1981 and Chk2 at Thr68.	Hydrogen Peroxide	101-118	checkpoint kinase 2	Homo sapiens	222-226	
30254210-5	2019	To further explore the functional relationship between PARP1 and CHK2, this study employed H2O2 to induce an oxidative DNA damage response in cells.	Hydrogen Peroxide	91-95	checkpoint kinase 2	Homo sapiens	65-69	
28751929-6	2017	H2O2-induced activation of checkpoint kinase 2 (Chk2) was significantly attenuated after the preconditioning of BBR.	Hydrogen Peroxide	0-4	checkpoint kinase 2	Homo sapiens	48-52