PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14670823-3	2004	To elucidate factors responsible for UC motor dysfunction, we examined the role of hydrogen peroxide (H(2)O(2)) in the decrease of NKA-induced response of HSCCM.	Hydrogen Peroxide	83-100	tachykinin precursor 1	Homo sapiens	131-134	
6183713-4	1982	If the extracts were oxidized with hydrogen peroxide before chromatography, all the immunoreactivity was found in the peak corresponding to oxidized substance P.	Hydrogen Peroxide	35-52	tachykinin precursor 1	Homo sapiens	149-160	
20121248-8	2010	To elucidate the products of the copper(II)-catalyzed oxidation of the (1-2,10-21)NPgamma and Ac-(1-2,10-21)NPgamma fragments of neuropeptide gamma, the liquid chromatography-mass spectrometry method and the use of Cu(II)/hydrogen peroxide as a model oxidizing system were employed.	Hydrogen Peroxide	222-239	tachykinin precursor 1	Homo sapiens	129-147	
2459200-2	1988	The neuropeptide substance P (SP), which has been suggested to mediate neurogenic inflammation, induces in human neutrophils the activation of the respiratory burst measured as O2 consumption and H2O2 production, and a cytochalasin B-dependent secretion of specific and azurophilic granules.	Hydrogen Peroxide	196-200	tachykinin precursor 1	Homo sapiens	17-28	
2459200-2	1988	The neuropeptide substance P (SP), which has been suggested to mediate neurogenic inflammation, induces in human neutrophils the activation of the respiratory burst measured as O2 consumption and H2O2 production, and a cytochalasin B-dependent secretion of specific and azurophilic granules.	Hydrogen Peroxide	196-200	tachykinin precursor 1	Homo sapiens	30-32	
32562941-4	2020	Those pPt-PEG NPs are able to produce reactive oxygen species (ROS) by triggering water decomposition under electric field, independent of O2 and H2O2 contents in the tumor.	Hydrogen Peroxide	146-150	tachykinin precursor 1	Homo sapiens	6-9	
21103419-6	2010	PAF and SP activate peripheral blood leukocytes inducing the production of H(2)O(2).	Hydrogen Peroxide	75-83	tachykinin precursor 1	Homo sapiens	8-10	
20435351-8	2010	To elucidate the products of the copper(II)-catalyzed oxidation of the neurokinin A and Ac-neurokinin A, liquid chromatography-mass spectrometry (LC-MS) method and Cu(II)/hydrogen peroxide as a model oxidizing system were employed.	Hydrogen Peroxide	171-188	tachykinin precursor 1	Homo sapiens	71-83	
16033908-1	2005	We have previously shown that sigmoid circular muscle cells from patients with ulcerative colitis (UC) exhibit reduced contraction and Ca2+ signaling in response to the neurotransmitter neurokinin A (NKA) and that IL-1beta and H2O2 may contribute to these reduced responses in UC.	Hydrogen Peroxide	227-231	tachykinin precursor 1	Homo sapiens	200-203	
14670823-7	2004	The decreased Ca(2+) signal and contraction in response to NKA or thapsigargin were partly recovered in the presence of H(2)O(2) scavenger catalase, suggesting involvement of H(2)O(2) in UC-induced dysmotility.	Hydrogen Peroxide	120-128	tachykinin precursor 1	Homo sapiens	59-62	
14670823-7	2004	The decreased Ca(2+) signal and contraction in response to NKA or thapsigargin were partly recovered in the presence of H(2)O(2) scavenger catalase, suggesting involvement of H(2)O(2) in UC-induced dysmotility.	Hydrogen Peroxide	175-183	tachykinin precursor 1	Homo sapiens	59-62	
14670823-11	2004	We conclude that H(2)O(2) may contribute to reduction of NKA-induced Ca(2+) release from intracellular Ca(2+) stores in UC and contribute to the observed colonic motor dysfunction.	Hydrogen Peroxide	17-25	tachykinin precursor 1	Homo sapiens	57-60	
10380907-0	1999	Substance P primes the formation of hydrogen peroxide and nitric oxide in human neutrophils.	Hydrogen Peroxide	36-53	tachykinin precursor 1	Homo sapiens	0-11	
12763764-5	2003	Endothelial production of H2O2 was quantified in bradykinin- or substance P-stimulated intact blood vessels by ESR spectroscopy.	Hydrogen Peroxide	26-30	tachykinin precursor 1	Homo sapiens	64-75	
10380907-4	1999	Our results indicate that SP primes two distinct pathways with respect to the induction of reactive oxygen species in the human neutrophil: the production of superoxide anion and hydrogen peroxide by the calmodulin-dependent NADPH oxidase, and the generation of NO by a constitutive NO synthase.	Hydrogen Peroxide	179-196	tachykinin precursor 1	Homo sapiens	26-28	
10380907-6	1999	These results give insight into distinct signal transduction pathways in the SP-primed neutrophil with respect to the formation of superoxide anion, hydrogen peroxide, and NO.	Hydrogen Peroxide	149-166	tachykinin precursor 1	Homo sapiens	77-79	
2162461-4	1990	When the NKA-LI was oxidized with hydrogen peroxide and rechromatographed, the immunoreactivity coeluted with NPK sulfoxide.	Hydrogen Peroxide	34-51	tachykinin precursor 1	Homo sapiens	9-12	
2162461-4	1990	When the NKA-LI was oxidized with hydrogen peroxide and rechromatographed, the immunoreactivity coeluted with NPK sulfoxide.	Hydrogen Peroxide	34-51	tachykinin precursor 1	Homo sapiens	110-113