PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21922195-5 2012 Higher basal, IR, and hydrogen peroxide-induced polymer levels were observed in Cdk5(KD) compared to Control cells. Hydrogen Peroxide 22-39 cyclin dependent kinase 5 Homo sapiens 80-84 26206088-6 2016 Lentiviral transduction assay shows that knockdown of Cdk5 or overexpression of CHIP(S20A), but not CHIP(WT), attenuates tAIF-mediated neuronal cell death induced by hydrogen peroxide. Hydrogen Peroxide 166-183 cyclin dependent kinase 5 Homo sapiens 54-58 23646926-8 2013 In addition, we found that there were no obvious changes of Cyclin-dependent kinase 5 (CDK5) expression (responsible for tau phosphorylation) and of p35 cleavage, the regulatory subunit of CDK5 in H2O2-treated HEK293/Tau cells. Hydrogen Peroxide 197-201 cyclin dependent kinase 5 Homo sapiens 189-193 12214088-6 2000 However, the H2O2-treated cells also manifested increased expression of growth and sprouting molecules, including GAP-43, nitric oxide synthase 3, neuronal thread protein (NTP; approximately 17 kD and approximately 21 kD forms), proliferating cell nuclear antigen, and phospho-Erk MAPK, and normal levels of the AD-associated approximately 41 kD NTP species, cyclin dependent kinase 5 (cdk-5), and phospho-tau. Hydrogen Peroxide 13-17 cyclin dependent kinase 5 Homo sapiens 359-384 18490454-6 2008 Moreover, Cdk5 (cyclin-dependent kinase 5), a proline-directed Ser/Thr kinase, additionally increases p53 stability via post-translational modification of p53 in response to hydrogen peroxide. Hydrogen Peroxide 174-191 cyclin dependent kinase 5 Homo sapiens 10-14 18490454-6 2008 Moreover, Cdk5 (cyclin-dependent kinase 5), a proline-directed Ser/Thr kinase, additionally increases p53 stability via post-translational modification of p53 in response to hydrogen peroxide. Hydrogen Peroxide 174-191 cyclin dependent kinase 5 Homo sapiens 16-41 18490454-9 2008 Our results show that c-Abl and Cdk5 cooperatively regulate maximal activation of p53, resulting in neuronal death in response to oxidative stress by hydrogen peroxide. Hydrogen Peroxide 150-167 cyclin dependent kinase 5 Homo sapiens 32-36 12214088-6 2000 However, the H2O2-treated cells also manifested increased expression of growth and sprouting molecules, including GAP-43, nitric oxide synthase 3, neuronal thread protein (NTP; approximately 17 kD and approximately 21 kD forms), proliferating cell nuclear antigen, and phospho-Erk MAPK, and normal levels of the AD-associated approximately 41 kD NTP species, cyclin dependent kinase 5 (cdk-5), and phospho-tau. Hydrogen Peroxide 13-17 cyclin dependent kinase 5 Homo sapiens 386-391 12214088-7 2000 In addition, the H2O2-treated cells had increased levels of p25, the catalytically active and stable cleavage product of p35, which regulates cdk-5 activity. Hydrogen Peroxide 17-21 cyclin dependent kinase 5 Homo sapiens 142-147