PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22094255-2 2011 We demonstrate that inducing cellular oxidative stress by hydrogen peroxide treatment recruits DNA methyltransferase 1 (DNMT1) to damaged chromatin. Hydrogen Peroxide 58-75 DNA methyltransferase 1 Homo sapiens 95-118 33761969-2 2021 We have previously shown that DNA methyltransferase (DNMT) activity can be inhibited by sublethal doses of hydrogen peroxide (H2O2). Hydrogen Peroxide 107-124 DNA methyltransferase 1 Homo sapiens 30-51 33761969-2 2021 We have previously shown that DNA methyltransferase (DNMT) activity can be inhibited by sublethal doses of hydrogen peroxide (H2O2). Hydrogen Peroxide 107-124 DNA methyltransferase 1 Homo sapiens 53-57 33761969-2 2021 We have previously shown that DNA methyltransferase (DNMT) activity can be inhibited by sublethal doses of hydrogen peroxide (H2O2). Hydrogen Peroxide 126-130 DNA methyltransferase 1 Homo sapiens 30-51 33761969-2 2021 We have previously shown that DNA methyltransferase (DNMT) activity can be inhibited by sublethal doses of hydrogen peroxide (H2O2). Hydrogen Peroxide 126-130 DNA methyltransferase 1 Homo sapiens 53-57 26165613-7 2015 H2O2 and ONOO(-) decreased Dnmt1 expression in CD4(+) T cells and caused the upregulation of genes known to be suppressed by DNA methylation in patients with lupus and animal models of SLE. Hydrogen Peroxide 0-4 DNA methyltransferase 1 Homo sapiens 27-32 24577881-7 2014 RESULTS: H2 O2 and ONOO(-) inhibited ERK pathway signaling in T cells by inhibiting the upstream regulator protein kinase Cdelta, decreased DNMT-1 levels, and caused demethylation and overexpression of genes previously shown to be suppressed by DNA methylation in T cells from patients with active lupus. Hydrogen Peroxide 9-14 DNA methyltransferase 1 Homo sapiens 140-146 23618814-8 2013 Furthermore, H2O2 treatment resulted in up-regulation of DNA methyltransferase 1 (DNMT1) and histone deacetylase 1 (HDAC1) expression and activity, and enhanced the association between DNMT1 and HDAC1. Hydrogen Peroxide 13-17 DNA methyltransferase 1 Homo sapiens 57-80 30954555-5 2019 Sublethal dosage of H2O2 treatment decrease E-cadherin, increase DNMT1, HDAC1, Snail, Slug and enrich H3K9me3 and H3K27me3 in the CDH1 promoter. Hydrogen Peroxide 20-24 DNA methyltransferase 1 Homo sapiens 65-70 30954555-7 2019 DNMT inhibitor, AZA prevented the H2O2 induced promoter-CpG-island methylation of CDH1. Hydrogen Peroxide 34-38 DNA methyltransferase 1 Homo sapiens 0-4 30548332-6 2019 Inhibition or knockdown of JAK2 reduces the H2 O2 -induced chromatin interaction of MSH2, MSH6, DNMT1, and PRC2 members, reduces H2 O2 -induced global increase in trimethylation of lysine 27 of histone H3 (H3K27me3), and abrogates oxidative damage-induced transcriptional repression of candidate TSGs. Hydrogen Peroxide 44-49 DNA methyltransferase 1 Homo sapiens 96-101 29131266-13 2017 Finally, both the mRNA level and protein level of DNMT1 increased in H2O2 simulated endometrial cells. Hydrogen Peroxide 69-73 DNA methyltransferase 1 Homo sapiens 50-55 26186941-5 2016 Hydrogen peroxide treatment induces the interaction of MSH2-MSH6 with DNMT1, suggesting that the recruitment is through a protein-protein interaction. Hydrogen Peroxide 0-17 DNA methyltransferase 1 Homo sapiens 70-75 23618814-8 2013 Furthermore, H2O2 treatment resulted in up-regulation of DNA methyltransferase 1 (DNMT1) and histone deacetylase 1 (HDAC1) expression and activity, and enhanced the association between DNMT1 and HDAC1. Hydrogen Peroxide 13-17 DNA methyltransferase 1 Homo sapiens 82-87 23618814-8 2013 Furthermore, H2O2 treatment resulted in up-regulation of DNA methyltransferase 1 (DNMT1) and histone deacetylase 1 (HDAC1) expression and activity, and enhanced the association between DNMT1 and HDAC1. Hydrogen Peroxide 13-17 DNA methyltransferase 1 Homo sapiens 185-190 23671287-3 2013 Inhibition of the production of H2O2 by the addition of catalase blocked the ability of this group of compounds to inhibit DNA methyltransferase (DNMT) activity. Hydrogen Peroxide 32-36 DNA methyltransferase 1 Homo sapiens 123-144 23671287-3 2013 Inhibition of the production of H2O2 by the addition of catalase blocked the ability of this group of compounds to inhibit DNA methyltransferase (DNMT) activity. Hydrogen Peroxide 32-36 DNA methyltransferase 1 Homo sapiens 146-150 22094255-2 2011 We demonstrate that inducing cellular oxidative stress by hydrogen peroxide treatment recruits DNA methyltransferase 1 (DNMT1) to damaged chromatin. Hydrogen Peroxide 58-75 DNA methyltransferase 1 Homo sapiens 120-125