PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21606925-10	2011	ML-7 and PP2 (MLCK and Src kinase inhibitors) attenuated hydrogen peroxide-induced barrier dysfunction, tight junction disruption and reorganization of actin cytoskeleton.	Hydrogen Peroxide	57-74	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	9-12	
29326556-7	2017	In parallel, we found that caveolin-1 (Cav1) is phosphorylated in response to H2O2 and that this is reversed by the Src kinase inhibitor 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).	Hydrogen Peroxide	78-82	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	202-205	
29326556-8	2017	PP2 also abrogated the H2O2-induced increase in AQP4 surface levels, suggesting that  the phosphorylation of tyrosine-14 of Cav1 regulates  this  process.	Hydrogen Peroxide	23-27	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	0-3	
20378826-7	2010	Promotion of cell migration by hydrogen peroxide was attenuated by LY294002 and PP2.	Hydrogen Peroxide	31-48	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	80-83	
16814101-3	2006	This H2O2-induced kinase activation was significantly attenuated by a Src kinase inhibitor PP2, or by transient transfection of carboxyl-terminal Src kinase (CSK) that maintained Src in the dormant form.	Hydrogen Peroxide	5-9	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	91-94	
17010316-1	2006	Recently we demonstrated that PP2 (4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine), a potent and selective inhibitor of the Src-family tyrosine kinase, markedly enhanced Ras-independent activation of Raf-1 by the combination of phorbol myristate acetate (PMA) and hydrogen peroxide (H(2)O(2)).	Hydrogen Peroxide	282-299	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	30-33	
16998541-10	2006	Moreover, H2O2-induced PKB phosphorylation was associated with increased tyrosine phosphorylation of c-Src and Pyk2 in an AG1024- and PP2-inhibitable manner.	Hydrogen Peroxide	10-14	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	134-137	
11278982-6	2001	Consistent with this observation, H(2)O(2) stimulated EGFR tyrosine phosphorylation and complex formation with Shc-Grb2 that was abolished by PP2, implicating Src in H(2)O(2)-induced EGFR activation.	Hydrogen Peroxide	34-42	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	142-145	
16513647-9	2006	In addition, Src inhibitor PP2 caused nuclear accumulation of Nrf 2 in normal and hydrogen peroxide-treated cells but had no effect on localization of mutant Nrf 2Y568A.	Hydrogen Peroxide	82-99	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	27-30	
12682076-8	2003	On the contrary, PP2 (4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazole[3,4-d]pyrimidine), an inhibitor of Src kinase, completely prevents DEM- and H2O2-induced AKT activation but has no effect on the pathway of ERKs.	Hydrogen Peroxide	145-149	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	17-20	
11278982-6	2001	Consistent with this observation, H(2)O(2) stimulated EGFR tyrosine phosphorylation and complex formation with Shc-Grb2 that was abolished by PP2, implicating Src in H(2)O(2)-induced EGFR activation.	Hydrogen Peroxide	166-174	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	142-145	
11402496-4	2001	Genistein and PP2 additionally prevent Fc gamma R-triggered hydrogen peroxide generation.	Hydrogen Peroxide	60-77	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	14-17	
10952984-4	2000	In contrast, the injury of endothelial cells mediated by H(2)O(2) is inhibited by PP2, a selective specific inhibitor for protein-tyrosine kinase Src.	Hydrogen Peroxide	57-65	neuropeptide Y receptor Y6 (pseudogene)	Homo sapiens	82-85