PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17217916-4 2007 Studies performed to analyze the levels of c-fos mRNA, a gene whose expression is modulated by the redox state, demonstrated that only high, apoptotic concentrations of TGF-beta(2) (100 pg/ml) produced an increase in the mRNA levels of this gene, the level of induction being similar to that found when cells were incubated in the presence of hydrogen peroxide. Hydrogen Peroxide 343-360 transforming growth factor beta 2 Homo sapiens 169-180 35198094-11 2022 Meanwhile, we observed that the expression of TGF-beta2, p-AKT, and p-GSK-3beta was upregulated in H2O2-treated ARPE-19 cells and downregulated in luteolin-treated cells, revealing that luteolin inhibited the activation of the AKT/GSK-3beta pathway. Hydrogen Peroxide 99-103 transforming growth factor beta 2 Homo sapiens 46-55 32980322-4 2020 In our research, we investigated the regulatory mechanisms and potential effects of TGF-beta1 & TGF-beta2 in hydrogen peroxide (H2O2)-stimulated oxidative stress of RGCs in vitro. Hydrogen Peroxide 109-126 transforming growth factor beta 2 Homo sapiens 96-105 25068653-10 2014 Downregulation of TGF-beta1 and TGF-beta2 by siRNA technology abolished the H2O2-induced conversion. Hydrogen Peroxide 76-80 transforming growth factor beta 2 Homo sapiens 32-41 19444386-0 2010 Hydrogen peroxide-induced cellular apoptosis is mediated by TGF-beta2 signaling pathway in cultured human lens epithelial cells. Hydrogen Peroxide 0-17 transforming growth factor beta 2 Homo sapiens 60-69 19444386-1 2010 The objective of this study was to investigate the signaling characteristics of transforming growth factor-beta2 (TGF-beta2) and the Smads (Caenorhabditis elegans, Sma; Drosophila mothers against dpp, Mad) signal pathway of cellular apoptosis induced by hydrogen peroxide with human lens epithelial cells (HLECs). Hydrogen Peroxide 254-271 transforming growth factor beta 2 Homo sapiens 114-123 19444386-10 2010 Our study demonstrated that the TGF-beta2 signal pathway participated in the apoptotic signal transfer and might be an initiator of cellular apoptosis of HLECs after incubation with hydrogen peroxide. Hydrogen Peroxide 182-199 transforming growth factor beta 2 Homo sapiens 32-41 19444386-11 2010 Interruption of the TGF-beta2 signal pathway could partially protect HLECs from apoptosis induced by incubation with hydrogen peroxide. Hydrogen Peroxide 117-134 transforming growth factor beta 2 Homo sapiens 20-29 32980322-4 2020 In our research, we investigated the regulatory mechanisms and potential effects of TGF-beta1 & TGF-beta2 in hydrogen peroxide (H2O2)-stimulated oxidative stress of RGCs in vitro. Hydrogen Peroxide 128-132 transforming growth factor beta 2 Homo sapiens 96-105 32980322-6 2020 Results of protein expression showed that TGF-beta1 & TGF-beta2 was upregulated in RGCs after H2O2 stimulation. Hydrogen Peroxide 94-98 transforming growth factor beta 2 Homo sapiens 54-63 32132577-4 2020 Hydrogen peroxide (H2O2) not only upregulated alpha-SMA but also enhanced the effect of TGF-beta2 on the expression of Snail and Slug. Hydrogen Peroxide 0-17 transforming growth factor beta 2 Homo sapiens 88-97 32132577-4 2020 Hydrogen peroxide (H2O2) not only upregulated alpha-SMA but also enhanced the effect of TGF-beta2 on the expression of Snail and Slug. Hydrogen Peroxide 19-23 transforming growth factor beta 2 Homo sapiens 88-97 30639613-4 2019 We show that TGF-beta2 drives expression of catalase to reduce the amount of H2O2 produced by T. annulata-transformed bovine macrophages, as well as by human lung (A549) and colon cancer (HT-29) cell lines. Hydrogen Peroxide 77-81 transforming growth factor beta 2 Homo sapiens 13-22