PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16289033-2	2005	In this study, we found that levels of MKP-1 expression were transiently decreased within 3h, followed by an increase 6-9h after H2O2-induced oxidative stress in human neuroblastoma SH-SY5Y cells.	Hydrogen Peroxide	129-133	dual specificity phosphatase 1	Homo sapiens	39-44	
20547488-2	2010	DUSP1/MKP-1 is implicated in cellular protection against a variety of genotoxic insults including hydrogen peroxide, ionizing radiation, and cisplatin, but its role in the interplay between different MAPK pathways in determining cell death and survival is not fully understood.	Hydrogen Peroxide	98-115	dual specificity phosphatase 1	Homo sapiens	0-5	
20547488-2	2010	DUSP1/MKP-1 is implicated in cellular protection against a variety of genotoxic insults including hydrogen peroxide, ionizing radiation, and cisplatin, but its role in the interplay between different MAPK pathways in determining cell death and survival is not fully understood.	Hydrogen Peroxide	98-115	dual specificity phosphatase 1	Homo sapiens	6-11	
27837091-5	2017	The defect of UV-B-induced stomatal closure in mpk6 mutants was rescued by exogenous NO but not by exogenous H2O2 Furthermore, double mutant mkp1/mpk6 and the single mutant mpk6 showed the same responses to UV-B in terms of either stomatal movement or H2O2 and NO production.	Hydrogen Peroxide	252-256	dual specificity phosphatase 1	Homo sapiens	141-145	
21822690-8	2012	This decreased activation of JNK-1 in stressed, contact-inhibited cells did not appear to be dependent upon increased expression of MKP-1; however, over-expression of MKP-1 was sufficient to result in a slight decrease in H2O2-stimulated PARP cleavage.	Hydrogen Peroxide	222-226	dual specificity phosphatase 1	Homo sapiens	167-172	
18490444-6	2008	HuR or NF90 silencing significantly diminished the H(2)O(2)-stimulated MKP-1 mRNA stability; HuR silencing also markedly decreased MKP-1 translation.	Hydrogen Peroxide	51-59	dual specificity phosphatase 1	Homo sapiens	71-76	
17086094-5	2006	Expression of MAPK phosphatase-1 (MKP-1) also was upregulated by H2O2, but this was not affected by pitavastatin.	Hydrogen Peroxide	65-69	dual specificity phosphatase 1	Homo sapiens	14-32	
17086094-5	2006	Expression of MAPK phosphatase-1 (MKP-1) also was upregulated by H2O2, but this was not affected by pitavastatin.	Hydrogen Peroxide	65-69	dual specificity phosphatase 1	Homo sapiens	34-39	
9119028-13	1997	Furthermore, H2O2 likely induced the expression of CL100/PAC1/MKP-1, a dual specificity phosphatase which has been implicated in ERK and JNK inactivation in the nucleus.	Hydrogen Peroxide	13-17	dual specificity phosphatase 1	Homo sapiens	51-56	
9119028-13	1997	Furthermore, H2O2 likely induced the expression of CL100/PAC1/MKP-1, a dual specificity phosphatase which has been implicated in ERK and JNK inactivation in the nucleus.	Hydrogen Peroxide	13-17	dual specificity phosphatase 1	Homo sapiens	62-67	
12186877-7	2002	The antiapoptotic effect of t-RA on H(2)O(2)-induced apoptosis in several cell types was correlated with the inducibility of MKP-1 by t-RA.	Hydrogen Peroxide	36-44	dual specificity phosphatase 1	Homo sapiens	125-130	
12186877-9	2002	Furthermore, overexpression of MKP-1 inhibited H(2)O(2)-induced JNK phosphorylation and apoptosis.	Hydrogen Peroxide	47-55	dual specificity phosphatase 1	Homo sapiens	31-36	
11689710-3	2001	Here we show that MKP-1 mRNA was potently induced by arsenite and ultraviolet light and modestly increased by heat shock and hydrogen peroxide.	Hydrogen Peroxide	125-142	dual specificity phosphatase 1	Homo sapiens	18-23