PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16840785-6	2006	Decreased insolubilization of Hsp25 in MK2-deficient cells correlates with increased resistance against arsenite, H2O2, and sublethal heat shock treatment and with decreased apoptosis.	Hydrogen Peroxide	114-118	MAPK activated protein kinase 2	Homo sapiens	39-42	
26169728-0	2015	Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to hydrogen peroxide-induced oxidative stress in human hepatobiliary cancer cells.	Hydrogen Peroxide	83-100	MAPK activated protein kinase 2	Homo sapiens	0-59	
14517288-7	2003	These effects were mimicked by hydrogen peroxide treatment (oxidative stress), which resulted in the phosphorylation of endogenous MK2.	Hydrogen Peroxide	31-48	MAPK activated protein kinase 2	Homo sapiens	131-134	
14517288-8	2003	In addition, hydrogen peroxide treatment enhanced the cytoplasmic binding of HuR to the ARE(uPA), which was abrogated in cells transfected with MK2-K76R.	Hydrogen Peroxide	13-30	MAPK activated protein kinase 2	Homo sapiens	144-147	
12847121-8	2003	Our studies also showed that the phosphorylation of MAPKAPK2 by H(2)O(2) followed a parallel time-dependent pattern and that SB203580 abolished this phosphorylation.	Hydrogen Peroxide	64-72	MAPK activated protein kinase 2	Homo sapiens	52-60	
10593919-6	1999	In vitro kinase analyses revealed that 1 mM H(2)O(2) stimulated the activity of JNK by approximately 8-fold, MAPKAP-K2 (the downstream target of p38 MAP kinase) by approximately 12-fold and that of PKB by up to 34-fold.	Hydrogen Peroxide	44-52	MAPK activated protein kinase 2	Homo sapiens	109-118	
10567216-3	1999	Treatment of human platelets with H(2)O(2) stimulated SAPK2a and its downstream target mitogen-activated protein kinase-activated protein kinase-2 (MAPKAP-K2).	Hydrogen Peroxide	34-42	MAPK activated protein kinase 2	Homo sapiens	87-146	
10567216-3	1999	Treatment of human platelets with H(2)O(2) stimulated SAPK2a and its downstream target mitogen-activated protein kinase-activated protein kinase-2 (MAPKAP-K2).	Hydrogen Peroxide	34-42	MAPK activated protein kinase 2	Homo sapiens	148-157	
30066830-3	2018	In the present study, through a series of reverse transcription-quantitative polymerase chain reaction (RT-qPCR), western blot and immunofluorescence assay, it was found that MK2 and tumor necrosis factor (TNF)-alpha/interleukin (IL)-1beta were elevated in patients with SCI and in H2O2-treated C8-D1A cells.	Hydrogen Peroxide	282-286	MAPK activated protein kinase 2	Homo sapiens	175-178	
29125882-4	2018	In the present study, we found that an elevated MK2 but a decreased miR-137 was expressed in serum specimens of patients with spinal cord injury and in hydrogen peroxide-treated C8-D1A and C8-B4 cells.	Hydrogen Peroxide	152-169	MAPK activated protein kinase 2	Homo sapiens	48-51	
26169728-5	2015	In addition to MK2 and Hsp27 overexpression in primary liver tumors compared to adjacent nontumorous tissues, the MK2/Hsp27 pathway is activated by hydrogen peroxide-induced oxidative stress in hepatobiliary cancer cells.	Hydrogen Peroxide	148-165	MAPK activated protein kinase 2	Homo sapiens	114-117	
25542757-4	2015	In the present study, we first found that treatment of A549 cells with hydrogen peroxide induced the activation of MAPKAPK-2 and phosphorylation of EGFR at Ser1047 within 30 min.	Hydrogen Peroxide	71-88	MAPK activated protein kinase 2	Homo sapiens	115-124	
18440775-2	2008	VEGF-induced HSP27 phosphorylation at serines 15, 78 and 82, but whereas HSP27 phosphorylation induced by H2O2 and TNFalpha was completely blocked by the p38 kinase inhibitor, SB203580, VEGF-stimulated serine 82 phosphorylation was resistant to SB203580 and small interfering(si)RNA-mediated knockdown of p38 kinase and MAPKAPK2.	Hydrogen Peroxide	106-110	MAPK activated protein kinase 2	Homo sapiens	320-328	
24934860-4	2014	Additionally, the increased p38MAPK/MAPKAPK-2 activation persisted in H2O2-treated cells.	Hydrogen Peroxide	70-74	MAPK activated protein kinase 2	Homo sapiens	36-45	
27012093-1	2015	Human endometrium-derived mesenchymal stem cells (hMESC) under the sublethal oxidative stress induced by H2O2 activate both p53/p21/Rb and p38MAPK/MAPKAPK-2 pathways that are responsible for the induction of hMESC premature senescence (Borodkina et al., 2014).	Hydrogen Peroxide	105-109	MAPK activated protein kinase 2	Homo sapiens	147-156