PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9553143-4	1998	In this study P116, a ZAP-70-negative Jurkat T cell line, was used to investigate the role of ZAP-70 in mediating activation of Erk in response to H2O2.	Hydrogen Peroxide	147-151	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	94-100	
9553143-5	1998	Consistent with the hypothesis that ZAP-70 is required for activation of Erk in response to an oxidative stimulus, Erk1 and Erk2 could be rapidly activated in Jurkat cells but not in P116 cells upon addition of H2O2.	Hydrogen Peroxide	211-215	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	36-42	
9553143-6	1998	P116 cells became competent for H2O2-induced Erk activation upon stable transfection with wild-type ZAP-70.	Hydrogen Peroxide	32-36	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	100-106	
9553143-7	1998	An in vivo ZAP-70 substrate, SLP-76, implicated in Erk activation, also became rapidly tyrosine-phosphorylated in Jurkat cells, but not in P116 cells, upon treatment with H2O2.	Hydrogen Peroxide	171-175	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	11-17	
9553143-8	1998	Surprisingly, although ZAP-70 was required for H2O2-mediated Erk activation, Erk activation in response to T cell antigen receptor engagement did not require ZAP-70.	Hydrogen Peroxide	47-51	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	23-29	
9553143-9	1998	In addition to demonstrating a requirement for ZAP-70 in H2O2-stimulated Erk activation, these results provide the first evidence for the existence of a ZAP-70-independent pathway for Erk activation in T cells.	Hydrogen Peroxide	57-61	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	47-53	
8051172-7	1994	The T cell tyrosine kinase ZAP-70 was found to be highly responsive to UV and H2O2 treatment.	Hydrogen Peroxide	78-82	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	27-33	
8051172-0	1994	ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction.	Hydrogen Peroxide	73-77	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	0-6	
25287889-6	2015	We also find that ITAM binding to ZAP-70 and Syk is sensitive to the presence of H2O2 and these two cysteine residues are also necessary for inhibition by H2O2.	Hydrogen Peroxide	81-85	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	34-40	
25287889-6	2015	We also find that ITAM binding to ZAP-70 and Syk is sensitive to the presence of H2O2 and these two cysteine residues are also necessary for inhibition by H2O2.	Hydrogen Peroxide	155-159	zeta chain of T cell receptor associated protein kinase 70	Homo sapiens	34-40