PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24073824-8	2014	This increase was not caused by extracellular hydrogen peroxide (H2O2) produced by DUOX because both DUOX expression and extracellular H2O2 synthesis were decreased by Th1 cytokines.	Hydrogen Peroxide	135-139	negative elongation factor complex member C/D	Homo sapiens	168-171	
21956503-4	2012	We show that hydrogen peroxide-induced oxidative stress can cause a ~twofold decrease in the number of lymphocytes secreting the TH1 cytokines IFN-gamma and IL-2, as well as chemokines IL-8 and TNF-alpha.	Hydrogen Peroxide	13-30	negative elongation factor complex member C/D	Homo sapiens	129-132	
17588662-3	2008	We found that low-doses of H2O2 reduce the INF-gamma production of activated Th1 clones and potentiate the IL-4 secretion of activated Th2 clones.	Hydrogen Peroxide	27-31	negative elongation factor complex member C/D	Homo sapiens	77-80	
17977519-0	2008	Critical role of hydrogen peroxide in the differential susceptibility of Th1 and Th2 cells to tributyltin-induced apoptosis.	Hydrogen Peroxide	17-34	negative elongation factor complex member C/D	Homo sapiens	73-76	
21057930-2	2011	The output of an ELISpot assay is a formation of colored spots which appear at the sites of cells releasing cytokines, with each individual spot representing a single cytokine-releasing cell.We have shown that hydrogen peroxide-induced oxidative stress was causing ~twofold decrease in the number of lymphocytes secreting the TH1 cytokines IFN-gamma and IL-2, as well as chemokine IL-8 and cytokine TNF alpha.	Hydrogen Peroxide	210-227	negative elongation factor complex member C/D	Homo sapiens	326-329	
17588662-4	2008	These effects were not due to altered cell proliferation and are not transient, since the modified secretion profile was still retained after 1 week from H2O2 stimulation by both Th1 and Th2 cells.	Hydrogen Peroxide	154-158	negative elongation factor complex member C/D	Homo sapiens	179-182	
17588662-5	2008	H2O2 influence the profile of cytokine secretion in both Th1 and Th2.	Hydrogen Peroxide	0-4	negative elongation factor complex member C/D	Homo sapiens	57-60	
15937358-7	2005	In the system, the red spots corresponding to IL-2-secreting cells (Th1) were developed with horseradish peroxidase and amino-ethyl-carbazole/H2O2.	Hydrogen Peroxide	142-146	negative elongation factor complex member C/D	Homo sapiens	68-71	
16111680-8	2005	Diphenyleneiodonium (DPI)-inhibitable apical H2O2 production was similarly increased by the addition of Th1 or Th2 cytokines.	Hydrogen Peroxide	45-49	negative elongation factor complex member C/D	Homo sapiens	104-107	
11509600-7	2001	The reduction of Th1 cytokines, induced by H2O2, was predominantly observed in memory/effector (CD45RO(+)) T cells and correlated with a block in NF-kappaB activation.	Hydrogen Peroxide	43-47	negative elongation factor complex member C/D	Homo sapiens	17-20	
10782806-0	2000	Bucillamine suppresses human Th1 cell development by a hydrogen peroxide-independent mechanism.	Hydrogen Peroxide	55-72	negative elongation factor complex member C/D	Homo sapiens	29-32