PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25103559-7 2014 Knockdown of the autophagy regulatory proteins Beclin1 or ATG5 protected the cells from OSU-03012 and from [OSU-03012 + PDE5 inhibitor] toxicity. osu 88-91 autophagy related 5 Homo sapiens 58-62 25103559-7 2014 Knockdown of the autophagy regulatory proteins Beclin1 or ATG5 protected the cells from OSU-03012 and from [OSU-03012 + PDE5 inhibitor] toxicity. osu 108-111 autophagy related 5 Homo sapiens 58-62 20107314-5 2010 Knockdown of ATG5 or Beclin1 suppressed OSU-03012 enhanced MDA-7/IL-24-induced autophagy and blocked the lethal interaction between the two agents. osu 40-43 autophagy related 5 Homo sapiens 13-17 18216498-6 2008 OSU enhances the expression of ATG5 in a PERK-dependent fashion and promotes the ATG5-dependent formation of vesicles containing LC3, followed by a subsequent cleavage of cathepsin B and a cathepsin B-dependent formation of low pH intracellular vesicles; cathepsin B is activated and released into the cytosol, and genetic suppression of cathepsin B or AIF function significantly suppresses cell killing. osu 0-3 autophagy related 5 Homo sapiens 31-35 18216498-6 2008 OSU enhances the expression of ATG5 in a PERK-dependent fashion and promotes the ATG5-dependent formation of vesicles containing LC3, followed by a subsequent cleavage of cathepsin B and a cathepsin B-dependent formation of low pH intracellular vesicles; cathepsin B is activated and released into the cytosol, and genetic suppression of cathepsin B or AIF function significantly suppresses cell killing. osu 0-3 autophagy related 5 Homo sapiens 81-85