PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18216498-6 2008 OSU enhances the expression of ATG5 in a PERK-dependent fashion and promotes the ATG5-dependent formation of vesicles containing LC3, followed by a subsequent cleavage of cathepsin B and a cathepsin B-dependent formation of low pH intracellular vesicles; cathepsin B is activated and released into the cytosol, and genetic suppression of cathepsin B or AIF function significantly suppresses cell killing. osu 0-3 apoptosis inducing factor mitochondria associated 1 Homo sapiens 353-356