PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20714220-2 2010 In addition to global downregulation of cap-dependent protein synthesis mediated by the GCN2 and mTORC1 signaling pathways, a catabolic process autophagy is upregulated to provide internal building blocks and energy needed to sustain viability. cap 40-43 eukaryotic translation initiation factor 2 alpha kinase 4 Homo sapiens 88-92 21638082-6 2011 When tested for the role of PERK and GCN2 on basal translation from the HCV IRES under non-stressed condition, we found that basal translation from the HCV IRES was also favoured in the presence of PERK or GCN2 in MEFs over that of cap-dependent translation and was favoured in the presence of GCN2 but not PERK in Huh-7 cells. cap 232-235 eukaryotic translation initiation factor 2 alpha kinase 4 Homo sapiens 206-210 21638082-6 2011 When tested for the role of PERK and GCN2 on basal translation from the HCV IRES under non-stressed condition, we found that basal translation from the HCV IRES was also favoured in the presence of PERK or GCN2 in MEFs over that of cap-dependent translation and was favoured in the presence of GCN2 but not PERK in Huh-7 cells. cap 232-235 eukaryotic translation initiation factor 2 alpha kinase 4 Homo sapiens 206-210