PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27749759-6	2017	The sepsis-induced increase in 4E-BP1 was associated with enhanced formation of the eIF4E-eIF4G active cap-dependent complex, while the increased S6K1 was associated with increased phosphorylation of downstream targets S6 and eIF4B.	cap	103-106	eukaryotic translation initiation factor 4E	Mus musculus	84-89	
23434932-3	2013	In both streptozotocin (STZ)-treated mice and cells in culture exposed to hyperglycemic conditions, expression of 4E-BP1 and its interaction with the mRNA cap-binding protein eIF4E were enhanced in conjunction with downregulation of cap-dependent and concomitant upregulation of cap-independent mRNA translation, as assessed by a bicistronic luciferase reporter assay.	cap	155-158	eukaryotic translation initiation factor 4E	Mus musculus	175-180	
25524901-3	2015	We found that mouse mammary morphogenesis during pregnancy and lactation is accompanied by increased cap-binding capability of eIF4E and activation of the eIF4E-dependent translational apparatus, but only subtle oscillations in eIF4E abundance.	cap	101-104	eukaryotic translation initiation factor 4E	Mus musculus	127-132	
23269249-3	2013	It has been hypothesized that MAPK-interacting kinase 1 and 2 (Mnk1/2) promote cap-dependent translation by phosphorylating eIF4E at serine 209 (S209).	cap	79-82	eukaryotic translation initiation factor 4E	Mus musculus	124-129	
15388875-0	2004	Cap-binding activity of an eIF4E homolog from Leishmania.	cap	0-3	eukaryotic translation initiation factor 4E	Mus musculus	27-32	
20679220-1	2010	MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) are protein-serine/threonine kinases that are activated by ERK or p38 and phosphorylate eIF4E, which is involved in cap-dependent translation initiation.	cap	170-173	eukaryotic translation initiation factor 4E	Mus musculus	142-147	
18220364-5	2008	Hydrogen-deuterium exchange and electrospray mass spectrometry were applied to probe local dynamics of murine eIF4E in the apo and cap-bound forms.	cap	131-134	eukaryotic translation initiation factor 4E	Mus musculus	110-115	
23263185-5	2013	Here we show that genetically increasing the levels of eukaryotic translation initiation factor 4E (eIF4E) in mice results in exaggerated cap-dependent translation and aberrant behaviours reminiscent of autism, including repetitive and perseverative behaviours and social interaction deficits.	cap	138-141	eukaryotic translation initiation factor 4E	Mus musculus	55-98	
23263185-5	2013	Here we show that genetically increasing the levels of eukaryotic translation initiation factor 4E (eIF4E) in mice results in exaggerated cap-dependent translation and aberrant behaviours reminiscent of autism, including repetitive and perseverative behaviours and social interaction deficits.	cap	138-141	eukaryotic translation initiation factor 4E	Mus musculus	100-105	
23263185-7	2013	The autistic-like behaviours displayed by the eIF4E-transgenic mice are corrected by intracerebroventricular infusions of the cap-dependent translation inhibitor 4EGI-1.	cap	126-129	eukaryotic translation initiation factor 4E	Mus musculus	46-51	
11777913-1	2002	In resting cells, eIF4E-binding protein 1 (4E-BP1) binds to the eukaryotic initiation factor-4E (eIF-4E), preventing formation of a functional eIF-4F complex essential for cap-dependent initiation of translation.	cap	172-175	eukaryotic translation initiation factor 4E	Mus musculus	64-95	
11777913-1	2002	In resting cells, eIF4E-binding protein 1 (4E-BP1) binds to the eukaryotic initiation factor-4E (eIF-4E), preventing formation of a functional eIF-4F complex essential for cap-dependent initiation of translation.	cap	172-175	eukaryotic translation initiation factor 4E	Mus musculus	97-103