PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25772062-8 2015 The exposure of the cells to 0.5 mM enalapril and enalaprilat contributed to increase in IGF-IR and alpha2beta1 integrin receptor as well as TGF-beta1 and NF-kappaB p65 expressions. Enalaprilat 50-61 transforming growth factor beta 1 Homo sapiens 141-150 25772062-9 2015 Enalapril- and enalaprilat-dependent increase of collagen biosynthesis in fibroblasts results from increase of prolidase activity and expression, which may undergo through activation of alpha2beta1 integrin and IGF-IR signaling as well as upregulation of TGF-beta1 and NF-kappaB p65, the inhibitor of collagen gene expression. Enalaprilat 15-26 transforming growth factor beta 1 Homo sapiens 255-264 20637368-7 2010 Enalaprilat and valsartan partly lowered overproduction of TGF-beta1 mRNA and excreted protein of podocytes, whereas enalaprilat plus valsartan completely restored them to the level as control. Enalaprilat 0-11 transforming growth factor beta 1 Homo sapiens 59-68 11124597-6 2000 Enalaprilat completely reversed the stimulatory effects of CyA on CF collagen synthesis (CyA + enalaprilat 6.40 +/- 0.50% vs. CyA alone 8.33 +/- 0.56% vs. control 6.57 +/- 0.62% vs. enalaprilat alone 5.55 +/- 0.93%, p < 0.05) and PTC secretion of TGFbeta1 (0.71 +/- 0.11, 1.13 +/- 0.09, 0.89 +/- 0.07, and 0.67 +/- 0.09 ng/mg protein/day, respectively, p < 0.05). Enalaprilat 0-11 transforming growth factor beta 1 Homo sapiens 250-258