PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10942157-14 2000 Our data suggest that ACE inhibitors enalaprilat, ramiprilat, and fosinopril produce a significant ocular hypotensive effect in acute and chronic models of ocular hypertension in rabbits. Enalaprilat 37-48 angiotensin-converting enzyme Oryctolagus cuniculus 22-25 11578111-0 2001 Inhibition of serum angiotensin-converting enzyme in rabbits after intravenous administration of enalaprilat-loaded intact erythrocytes. Enalaprilat 97-108 angiotensin-converting enzyme Oryctolagus cuniculus 20-49 11578111-2 2001 In this study, the inhibition time courses of serum angiotensin-converting enzyme (ACE) activity after intravenous administration of enalaprilat encapsulated in intact erythrocytes was evaluated and compared with free drug, in a rabbit model. Enalaprilat 133-144 angiotensin-converting enzyme Oryctolagus cuniculus 52-81 11578111-2 2001 In this study, the inhibition time courses of serum angiotensin-converting enzyme (ACE) activity after intravenous administration of enalaprilat encapsulated in intact erythrocytes was evaluated and compared with free drug, in a rabbit model. Enalaprilat 133-144 angiotensin-converting enzyme Oryctolagus cuniculus 83-86 12651915-4 2003 Similar effects were obtained using CV-11974 (another AT1R blocker) and enalaprilat (another ACE inhibitor). Enalaprilat 72-83 angiotensin-converting enzyme Oryctolagus cuniculus 93-96 10588480-3 1999 Aortic segments were cultured in medium containing a broad concentration range of the ACE inhibitor enalaprilat (0-100 microM). Enalaprilat 100-111 angiotensin-converting enzyme Oryctolagus cuniculus 86-89 2983065-3 1985 Hydrolysis of BPAP (4.2 microM) was 64.1 +/- 3.3% at 37 degrees C and was significantly decreased (P less than .01) to 10.1 +/- 8.7% by the addition of the ACE inhibitor, MK422 (10(-6) M). Enalaprilat 171-176 angiotensin-converting enzyme Oryctolagus cuniculus 156-159 10350000-5 1999 With respect to structure-function, ACE inhibitor affinity was strongly correlated with drug lipophilicity (r = 0.944, p < 0.001 for all ACE inhibitors; r = 0.983, p < 0.001 without enalaprilat, quinaprilat and quinapril). Enalaprilat 188-199 angiotensin-converting enzyme Oryctolagus cuniculus 36-39 34775060-1 2022 Formulations on the base of an inhibitor of angiotensin-converting enzyme, enalaprilat, were prepared by the inclusion of the drug into calcium phosphate (CaP)-particles in situ, followed by the covering of the particles with 5 kDa chitosan or 72 kDa glycol chitosan and cross-linking with sodium tripolyphosphate. Enalaprilat 75-86 angiotensin-converting enzyme Oryctolagus cuniculus 44-73 9869501-6 1998 Angiotensin-converting enzyme (ACE) inhibition with enalaprilat revealed a larger, more rapid decrease in MAP in response to omega-CTX (-19 +/- 4 mm Hg from 65 +/- 1 mm Hg after 18 +/- 2 min; n = 6) compared with the control group. Enalaprilat 52-63 angiotensin-converting enzyme Oryctolagus cuniculus 0-29 9869501-6 1998 Angiotensin-converting enzyme (ACE) inhibition with enalaprilat revealed a larger, more rapid decrease in MAP in response to omega-CTX (-19 +/- 4 mm Hg from 65 +/- 1 mm Hg after 18 +/- 2 min; n = 6) compared with the control group. Enalaprilat 52-63 angiotensin-converting enzyme Oryctolagus cuniculus 31-34 7714339-8 1995 The conversion of BK into des-Arg9-BK was generally efficient, and the persistence and concentration of both peptides were increased in the presence of enalaprilat an inhibitor of the angiotensin converting enzyme (ACEI). Enalaprilat 152-163 angiotensin-converting enzyme Oryctolagus cuniculus 184-213 7714339-8 1995 The conversion of BK into des-Arg9-BK was generally efficient, and the persistence and concentration of both peptides were increased in the presence of enalaprilat an inhibitor of the angiotensin converting enzyme (ACEI). Enalaprilat 152-163 angiotensin-converting enzyme Oryctolagus cuniculus 215-219 3503919-7 1987 Other ACE inhibitors such as captopril (0.1%) and enalaprilic acid (0.01%) also reduced IOP by 4.0 +/- 0.4 and 4.7 +/- 0.4 mmHg, respectively. Enalaprilat 50-66 angiotensin-converting enzyme Oryctolagus cuniculus 6-9 6199659-4 1984 This hydrolysis is inhibited by the angiotensin-converting enzyme inhibitors captopril, MK-422, and EDTA, and is dependent on the concentration of chloride ion. Enalaprilat 88-94 angiotensin-converting enzyme Oryctolagus cuniculus 36-65