PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1548425-3 1992 In the present study, we investigated the effects of tumor necrosis factor-alpha (TNF), interleukin-1 (IL-1), IL-4, and transforming growth factor-beta 1 (TGF-beta) on the adhesiveness of DMEC isolated from psoriatic plaques or normal skin for human peripheral blood mononuclear cells (PBMC). dmec 188-192 interleukin 1 alpha Homo sapiens 88-101 1548425-3 1992 In the present study, we investigated the effects of tumor necrosis factor-alpha (TNF), interleukin-1 (IL-1), IL-4, and transforming growth factor-beta 1 (TGF-beta) on the adhesiveness of DMEC isolated from psoriatic plaques or normal skin for human peripheral blood mononuclear cells (PBMC). dmec 188-192 interleukin 1 alpha Homo sapiens 103-107 1548425-5 1992 Pretreatment of DMEC from normal skin with human recombinant IL-1 or TNF alone or in combination for 8 h significantly (p less than 0.01) enhanced their capacity to adhere to human PBMC. dmec 16-20 interleukin 1 alpha Homo sapiens 61-65 1548425-6 1992 Similarly, treatment of normal DMEC with IL-4 also increased endothelial adhesiveness, although this cytokine required an incubation period of 24 h. In parallel studies, DMEC from psoriatic plaques were found to respond to the stimulatory effects of TNF, IL-1, and IL-4 in similar dose- and time-dependent manner. dmec 170-174 interleukin 1 alpha Homo sapiens 255-259