PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20686355-3	2010	In the latter case, Ets1 molecules bind to palindromic sequences in which two Ets-binding sites (EBS) are separated by four base pairs, for example in the promoters of stromelysin-1 and p53.	ethylbenzene	97-100	matrix metallopeptidase 3	Homo sapiens	168-181	
20686355-6	2010	Here we report the crystal structure of two Ets1 molecules bound to an EBS palindrome of the stromelysin-1 promoter DNA, providing a plausible explanation for the requirement of exon VII-encoded sequences for Ets1 cooperative DNA binding.	ethylbenzene	71-74	matrix metallopeptidase 3	Homo sapiens	93-106	
19465391-1	2009	The Stromelysin-1 gene promoter contains a palindrome of two Ets-binding sites (EBS) that bind the p51 and p42 isoforms of the human Ets-1-transcription factor.	ethylbenzene	80-83	matrix metallopeptidase 3	Homo sapiens	4-17	
19465391-5	2009	The differential stoichiometry of the two Ets-1 isoforms arises from the Stromelysin-1 EBS palindrome.	ethylbenzene	87-90	matrix metallopeptidase 3	Homo sapiens	73-86	
19022222-2	2009	In a study on the stromelysin-1 promoter, we showed that Ets-1 binds cooperatively to two Ets-binding sites (EBS) organized in palindrome, thereby circumventing the need for a binding partner to counteract autoinhibition.	ethylbenzene	109-112	matrix metallopeptidase 3	Homo sapiens	18-31	
19022222-6	2009	Thus, the cooperative binding model that we initially proposed for the stromelysin-1 promoter may be a general mechanism of Ets-1 binding to palindromic EBS separated by 4bp and a way to counteract binding site degeneracy.	ethylbenzene	153-156	matrix metallopeptidase 3	Homo sapiens	71-84	
16652151-2	2006	The Stromelysin-1 promoter is known to be transactivated by Ets proteins through palindromic head-to-head Ets binding sites (EBS), an unusual configuration among metalloproteinase promoters.	ethylbenzene	125-128	matrix metallopeptidase 3	Homo sapiens	4-17	
16652151-7	2006	Thus, it is the first demonstration, using this cellular model, that endogenously expressed Ets-1 is actually a main activator of the Stromelysin-1 promoter through its effective binding to the EBS palindrome.	ethylbenzene	194-197	matrix metallopeptidase 3	Homo sapiens	134-147