PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17551589-5 2007 METHODOLOGY/PRINCIPAL FINDINGS: Here, the role of Apis mellifera TOR (amTOR) in caste determination is examined by rapamycin/FK506 pharmacology and RNA interference (RNAi) gene knockdown. Tacrolimus 125-130 serine/threonine-protein kinase mTOR Apis mellifera 65-68 17551589-5 2007 METHODOLOGY/PRINCIPAL FINDINGS: Here, the role of Apis mellifera TOR (amTOR) in caste determination is examined by rapamycin/FK506 pharmacology and RNA interference (RNAi) gene knockdown. Tacrolimus 125-130 serine/threonine-protein kinase mTOR Apis mellifera 70-75 17551589-6 2007 We show that in queen-destined larvae, the TOR inhibitor rapamycin induces the development of worker characters that are blocked by the antagonist FK506. Tacrolimus 147-152 serine/threonine-protein kinase mTOR Apis mellifera 43-46