PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7679116-6 1993 Moreover, dephosphorylation of NF-ATp in cell extracts is inhibited by prior treatment of T cells with the immunosuppressive drugs cyclosporin A or FK506, which inhibit the phosphatase activity of calcineurin when complexed with their specific binding proteins, cyclophilin and FK506-binding protein. Tacrolimus 148-153 nuclear factor of activated T cells 1 Bos taurus 31-37 7679116-7 1993 This work identifies NF-ATp as a DNA-binding phosphoprotein and a target for the drug/immunophilin/calcineurin complexes thought to mediate the inhibition of interleukin-2 gene induction by cyclosporin A and FK506. Tacrolimus 208-213 nuclear factor of activated T cells 1 Bos taurus 21-27