PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14621743-4 1992 Exposure of tubular cells to high concentrations of FK506 or CyA (10, 50 and 100 microM) induced a time- and dose-dependent cell injury in vitro characterized by a direct cytotoxic effect on tubular cells as expressed by release of 3H-thymidine from prelabelled cells, N-acetyl-beta-D-glucosaminidase (NAG) release and cell detachment. Tacrolimus 52-57 O-GlcNAcase Homo sapiens 269-300 14621743-4 1992 Exposure of tubular cells to high concentrations of FK506 or CyA (10, 50 and 100 microM) induced a time- and dose-dependent cell injury in vitro characterized by a direct cytotoxic effect on tubular cells as expressed by release of 3H-thymidine from prelabelled cells, N-acetyl-beta-D-glucosaminidase (NAG) release and cell detachment. Tacrolimus 52-57 O-GlcNAcase Homo sapiens 302-305 14621744-7 1992 The concentrations of FK506 or CyA which induced ET-1 secretion by tubular cells and kidney cells were not cytolytic as assessed by N-acetyl-beta-D-glucosaminidase (NAG) release and lactic dehydrogenase (LDH) release. Tacrolimus 22-27 O-GlcNAcase Homo sapiens 165-168