PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7565718-9	1995	We have previously shown that growth of fks1 null mutants is highly sensitive to the calcineurin inhibitors FK506 and cyclosporin A.	Tacrolimus	108-113	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	40-44	
7542741-6	1995	CND1 is identical to the gene identified previously as FKS1, ETG1, and CWH53, cnd1 mutants are sensitive to FK506 and cyclosporin A and exhibit slow growth that is improved by the addition of osmotic stabilizing agents.	Tacrolimus	108-113	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	0-4	
7542741-6	1995	CND1 is identical to the gene identified previously as FKS1, ETG1, and CWH53, cnd1 mutants are sensitive to FK506 and cyclosporin A and exhibit slow growth that is improved by the addition of osmotic stabilizing agents.	Tacrolimus	108-113	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	55-59	
7542741-6	1995	CND1 is identical to the gene identified previously as FKS1, ETG1, and CWH53, cnd1 mutants are sensitive to FK506 and cyclosporin A and exhibit slow growth that is improved by the addition of osmotic stabilizing agents.	Tacrolimus	108-113	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	61-65	
7542741-6	1995	CND1 is identical to the gene identified previously as FKS1, ETG1, and CWH53, cnd1 mutants are sensitive to FK506 and cyclosporin A and exhibit slow growth that is improved by the addition of osmotic stabilizing agents.	Tacrolimus	108-113	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	71-76	
7542741-6	1995	CND1 is identical to the gene identified previously as FKS1, ETG1, and CWH53, cnd1 mutants are sensitive to FK506 and cyclosporin A and exhibit slow growth that is improved by the addition of osmotic stabilizing agents.	Tacrolimus	108-113	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	78-82	
7530227-0	1994	The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin A hypersensitivity and calcineurin-dependent growth.	Tacrolimus	80-85	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	10-14	
7530227-4	1994	We and others have defined the Saccharomyces cerevisiae FKS1 gene by recessive mutations resulting in 100-1000-fold hypersensitivity to FK506 and CsA (as compared to wild type), but which do not affect sensitivity to a variety of other antifungal drugs.	Tacrolimus	136-141	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	56-60	
7530227-12	1994	These data suggest that FKS1 provides a unique cellular function which, when absent, increases FK506 and CsA sensitivity by making the CNs (or a CN-dependent function) essential.	Tacrolimus	95-100	1,3-beta-D-glucan synthase	Saccharomyces cerevisiae S288C	24-28