PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34688813-0	2022	CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation.	Tacrolimus	92-102	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	0-6	
34688813-1	2022	AIM: The purpose of this study was to investigate the effect of CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in liver transplant recipients and donors on tacrolimus concentrations in the early stages after liver transplantation.	Tacrolimus	158-168	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	64-70	
34688813-7	2022	Regardless of the genotype of the matched donor, CYP3A7 rs10211, CYP3A4*1G (rs2242480), and CYP3A5*3 (rs776746) polymorphisms of recipients could affect tacrolimus concentrations.	Tacrolimus	153-163	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	49-55	
34688813-9	2022	CONCLUSION: The large inter-individual variation in tacrolimus concentrations in the early stages after liver transplantation is influenced by genetic polymorphisms of CYP3A7, CYP3A4, and CYP3A5.	Tacrolimus	52-62	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	168-174	
33649515-10	2021	CYP3A7*2, rs4646450, and rs3823812 are proposed as functional SNPs affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients.	Tacrolimus	77-87	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	0-6	
33515077-0	2021	Correction to: CYP3A5 and CYP3A7 genetic polymorphisms affect tacrolimus concentration in pediatric patients with nephrotic syndrome.	Tacrolimus	62-72	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	26-32	
29629825-4	2018	In addition to CYP3A5, other pharmacogenes associated with CYP3A activity, including CYP3A4, CYP3A7 and POR have also been identified as predictors of tacrolimus exposure.	Tacrolimus	151-161	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	93-99	
32034192-0	2020	Author Correction: Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients.	Tacrolimus	100-110	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	68-74	
31401678-0	2019	CYP3A5 and CYP3A7 genetic polymorphisms affect tacrolimus concentration in pediatric patients with nephrotic range proteinuria.	Tacrolimus	47-57	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	11-17	
31401678-1	2019	PURPOSE: The purpose of this study was to investigate the potential impact of CYP3A4, CYP3A5, and CYP3A7 polymorphisms on the concentration and efficacy of tacrolimus in a cohort of pediatric patients with nephrotic range proteinuria.	Tacrolimus	156-166	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	98-104	
31401678-5	2019	The CYP3A7 rs2257401 was also associated with the concentration of tacrolimus.	Tacrolimus	67-77	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	4-10	
31401678-7	2019	In addition, there were significant differences in tacrolimus concentration among CYP3A7 rs10211 G carriers and non-carriers; the latter had an almost twofold C0 of the former (101.8 vs 59.6, P = 0.0004).	Tacrolimus	51-61	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	82-88	
31401678-8	2019	CONCLUSIONS: Our study demonstrated the associations between CYP3A5*3, CYP3A7 rs2257401 and rs10211, and tacrolimus concentration in pediatric patients with nephrotic range proteinuria.	Tacrolimus	105-115	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	71-77	
31401678-9	2019	Children with CYP3A5*3 A, CYP3A7 rs2257401 C, and rs10211 G alleles might need a higher dose of tacrolimus.	Tacrolimus	96-106	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	26-32	
30584253-0	2018	Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients.	Tacrolimus	81-91	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	49-55	
30584253-10	2018	The combined set LMM showed that only CYP3A7 rs2257401 was associated with tacrolimus C0/D after adjusting for patient age, albumin, and creatinine.	Tacrolimus	75-85	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	38-44	
30584253-11	2018	The CYP3A7 rs2257401 genotype variant showed a significant difference on the tacrolimus C0/D in those expressing CYP3A5, showing its own effect.	Tacrolimus	77-87	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	4-10	
30584253-12	2018	The results suggest that CYP3A7 rs2257401 may serve as a significant genetic marker for tacrolimus pharmacokinetics in kidney transplantation.	Tacrolimus	88-98	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	25-31	
30156148-9	2018	Notably, the CYP3A7-CYP3A4 switch taking place during the very early life will affect tacrolimus metabolism.	Tacrolimus	86-96	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	13-26