PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11240954-3 2001 OBJECTIVE: The present study focused on the effects of topical tacrolimus treatment on epidermal CD1a+/FcepsilonRI+ DC populations in lesional AD. Tacrolimus 63-73 CD1a molecule Homo sapiens 97-101 11240954-8 2001 Finally, topical tacrolimus led to a progressive decrease in the IDEC population within the pool of CD1a+ epidermal DCs and also to a decrease in their CD36 expression, which is indicative of lower local inflammation. Tacrolimus 17-27 CD1a molecule Homo sapiens 100-104 11240954-9 2001 CONCLUSION: Epidermal CD1a+ DCs may represent a target for topical tacrolimus in the treatment of AD. Tacrolimus 67-77 CD1a molecule Homo sapiens 22-26 29520229-10 2018 Results: Topical tacrolimus significantly reversed high-dose UVB irradiation-induced epidermal LC reduction and CD1a+ cell increment in culture medium. Tacrolimus 17-27 CD1a molecule Homo sapiens 112-116 12091117-11 2002 In the sequential study, 5000 ng/mL FK506 before LPS addition resulted in a significant decrease in CD1a MFI and in the percentage of cells co-expressing CD83 and CD86. Tacrolimus 36-41 CD1a molecule Homo sapiens 100-104 20394493-7 2010 CD1a, CD11b and CCR7 expression were all significantly down-regulated after topical treatment with tacrolimus. Tacrolimus 99-109 CD1a molecule Homo sapiens 0-4