PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28849081-6 2017 The results of the present study demonstrated that lercanidipine and FK506 inhibited Ang II-induced cardiomyocyte hypertrophy, as evidenced by decreases in fetal gene (atrial natriuretic peptide and brain natriuretic peptide) expression levels and cell surface area. Tacrolimus 69-74 angiotensinogen Rattus norvegicus 85-91 22184128-3 2012 We investigated effects of two calcineurin inhibitors, cyclosporine A (CsA) and tacrolimus (FK506) (10-10-10-6 mol/L, 20 mins) on activation of MAP kinases and on growth, pro-fibrotic and pro-inflammatory responses in Ang II-stimulated rat cardiac fibroblasts. Tacrolimus 80-90 angiotensinogen Rattus norvegicus 218-224 22184128-5 2012 FK506, but not CsA, attenuated Ang II-stimulated MAP kinase activation. Tacrolimus 0-5 angiotensinogen Rattus norvegicus 31-37 16838106-6 2007 Ang II-induced apoptosis was inhibited by CV-11974 (Candesartan; Ang II type 1 [AT1] receptor blocker), SK&F96365, and FK506 (calcineurin inhibitor). Tacrolimus 123-128 angiotensinogen Rattus norvegicus 0-6 25752645-9 2015 Importantly, we showed that calcineurin-dependent NFAT3 nuclear translocation was essential to AngII-mediated IL-6 transcription, QL mimicked the effect of FK506, the calcineurin inhibitor, on suppression of IL-6 expression and stress fibres formation. Tacrolimus 156-161 angiotensinogen Rattus norvegicus 95-100 23657856-0 2013 Scavengers of reactive oxygen species, paracalcitol, RhoA, and Rac-1 inhibitors and tacrolimus inhibit angiotensin II-induced actions on glomerular permeability. Tacrolimus 84-94 angiotensinogen Rattus norvegicus 103-117