PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24049110-6 2013 We find FK506 treatment inhibits, whereas Fkbp4/5 overexpression promotes, miRNA-mediated stabilization of Ago2 expression. Tacrolimus 8-13 argonaute RISC catalytic component 2 Homo sapiens 107-111 24049110-7 2013 Simultaneous treatment with a lysosome inhibitor revealed the accumulation of unloaded Ago2 complexes in FK506-treated cells. Tacrolimus 105-110 argonaute RISC catalytic component 2 Homo sapiens 87-91 24049110-5 2013 Pharmacological inhibition of this interaction using FK506 or siRNA-mediated Fkbp4/5 depletion leads to decreased Ago2 protein levels. Tacrolimus 53-58 argonaute RISC catalytic component 2 Homo sapiens 114-118