PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18641302-5	2008	The ionomycin-mediated increase in HIF-1alpha protein levels was sensitive to the transcription inhibitor actinomycin D and to inhibitors of calcineurin, cyclosporin A (CsA), and FK506.	Tacrolimus	179-184	hypoxia inducible factor 1 subunit alpha	Homo sapiens	35-45	
18641302-7	2008	The HIF1A promoter activity was significantly increased in ionomycin-activated mast cells, and the promoter activity could be inhibited by CsA and FK506.	Tacrolimus	147-152	hypoxia inducible factor 1 subunit alpha	Homo sapiens	4-9	
17067582-0	2006	Immunophilin-ligands FK506 and CsA inhibit HIF1alpha expression by a VHL- and ubiquitin-independent mechanism.	Tacrolimus	21-26	hypoxia inducible factor 1 subunit alpha	Homo sapiens	43-52	
17067582-3	2006	We have evaluated the effect of the immunophilin ligands FK506 and cyclosporin A on HIF1alpha levels in different tumor cell lines.	Tacrolimus	57-62	hypoxia inducible factor 1 subunit alpha	Homo sapiens	84-93	
17190738-0	2006	FK506: an immunosuppressive agent preserving HIF-1 activity.	Tacrolimus	0-5	hypoxia inducible factor 1 subunit alpha	Homo sapiens	45-50	
17190738-7	2006	FK506 could preserve HIF-1 activity in donor organs subjected to hypoxia.	Tacrolimus	0-5	hypoxia inducible factor 1 subunit alpha	Homo sapiens	21-26