PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30746538-6	2019	PQ-induced DNA fragmentation in lymphocytes, reduction of oxidant scavenging capacity, expression of heme oxygenase 1 and inducible nitric oxide synthase in the lung, and elevation of serum transforming growth factor beta 1 were also inhibited.	Paraquat	0-2	heme oxygenase 1	Homo sapiens	101-153	
28083817-0	2018	Carnosic Acid Induces Anti-Inflammatory Effects in Paraquat-Treated SH-SY5Y Cells Through a Mechanism Involving a Crosstalk Between the Nrf2/HO-1 Axis and NF-kappaB.	Paraquat	51-59	heme oxygenase 1	Homo sapiens	141-145	
29411263-0	2018	Naringenin Exerts Anti-inflammatory Effects in Paraquat-Treated SH-SY5Y Cells Through a Mechanism Associated with the Nrf2/HO-1 Axis.	Paraquat	47-55	heme oxygenase 1	Homo sapiens	123-127	
29411263-10	2018	Therefore, NGN induced anti-inflammatory effects in PQ-treated SH-SY5Y cells by a mechanism associated with the Nrf2/HO-1 signaling pathway.	Paraquat	52-54	heme oxygenase 1	Homo sapiens	117-121	
28083817-6	2018	SH-SY5Y cells were pretreated for 12 h with CA at 1 muM before exposure to PQ for further 24 h. CA suppressed the PQ-induced alterations on the levels of interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha), and cyclooxygenase-2 (COX-2) through a mechanism involving the activation of the Nrf2/HO-1 axis.	Paraquat	114-116	heme oxygenase 1	Homo sapiens	311-315	
27686076-7	2017	We found that the CA-induced Nrf2-dependent HO-1 upregulation ameliorated, at least in part, the mitochondrial function in PQ-treated cells.	Paraquat	123-125	heme oxygenase 1	Homo sapiens	44-48	
23954820-5	2013	Moreover, treatments of PQ strongly inhibited the expression of Nrf2 and the downstream effectors, HO1 and NQO1.	Paraquat	24-26	heme oxygenase 1	Homo sapiens	99-102	
21735318-6	2011	In addition, we show that combined dopamine and paraquat treatment increases the expression of heme oxygenase-1, an antioxidant response protein.	Paraquat	48-56	heme oxygenase 1	Homo sapiens	95-111	
23546295-7	2013	The antioxidant potential of EA might be directly correlated with the increased expression of HO-1 and NQO1, whose expression may have surmounted the oxidative stress generated by PQ.	Paraquat	180-182	heme oxygenase 1	Homo sapiens	94-98