PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33333238-5 2021 Similarly, the levels of myeloperoxidase (MPO) and interleukin-1beta (IL-1beta) were lowered by Tollip overexpression in PQ-administrated mice. Paraquat 121-123 interleukin 1 beta Mus musculus 51-68 28249220-7 2017 In addition, the inflammatory responses induced by paraquat were inhibited after treatment with chloroquine, as indicated by the decreased number of leukocytes, the reduced levels of TNF-alpha, IL-1beta and IL-6 in the bronchoalveolar lavage fluid, the reduced NO content, and downregulation of iNOS expression in lung tissues. Paraquat 51-59 interleukin 1 beta Mus musculus 194-202 31495108-15 2019 After 48 hours, the expression of TNF-alpha, TGF-beta1, and IL-1beta in peripheral blood significantly increased by 39%, 45%, and 38%, respectively, in the PQ group (P<0.05) , but they significantly decreased by 31%, 13%, and 22%, respectively, in the OPCs+PQ group as compared with the PQ group (P<0.05) . Paraquat 156-158 interleukin 1 beta Mus musculus 60-68 31495108-15 2019 After 48 hours, the expression of TNF-alpha, TGF-beta1, and IL-1beta in peripheral blood significantly increased by 39%, 45%, and 38%, respectively, in the PQ group (P<0.05) , but they significantly decreased by 31%, 13%, and 22%, respectively, in the OPCs+PQ group as compared with the PQ group (P<0.05) . Paraquat 260-262 interleukin 1 beta Mus musculus 60-68 31495108-15 2019 After 48 hours, the expression of TNF-alpha, TGF-beta1, and IL-1beta in peripheral blood significantly increased by 39%, 45%, and 38%, respectively, in the PQ group (P<0.05) , but they significantly decreased by 31%, 13%, and 22%, respectively, in the OPCs+PQ group as compared with the PQ group (P<0.05) . Paraquat 260-262 interleukin 1 beta Mus musculus 60-68 31937024-9 2019 ELISA showed that TNF-alpha, IL-6 and IL-1beta contents in the cell supernatant of the PQ group were significantly higher than those of 0 mumol/L PQ group, especially in 0.03 and 0.06 mumol/L PQ exposed group (P<0.05) . Paraquat 87-89 interleukin 1 beta Mus musculus 38-46 31937024-12 2019 Western blot showed that compared with 0 mumol/L PQ group, the expression levels of M1 markers TNF-alpha, IL-6, IL-1beta, iNOS and CD86 were significantly increased in 0.03 and 0.06 mumol/L PQ exposed group, while the expression levels of M2 markers Arg-1 and CD206 protein were decreased in 0.06 and 0.12 mumol/L PQ exposed group (P<0.05) . Paraquat 49-51 interleukin 1 beta Mus musculus 112-120 31937024-12 2019 Western blot showed that compared with 0 mumol/L PQ group, the expression levels of M1 markers TNF-alpha, IL-6, IL-1beta, iNOS and CD86 were significantly increased in 0.03 and 0.06 mumol/L PQ exposed group, while the expression levels of M2 markers Arg-1 and CD206 protein were decreased in 0.06 and 0.12 mumol/L PQ exposed group (P<0.05) . Paraquat 190-192 interleukin 1 beta Mus musculus 112-120 31937024-12 2019 Western blot showed that compared with 0 mumol/L PQ group, the expression levels of M1 markers TNF-alpha, IL-6, IL-1beta, iNOS and CD86 were significantly increased in 0.03 and 0.06 mumol/L PQ exposed group, while the expression levels of M2 markers Arg-1 and CD206 protein were decreased in 0.06 and 0.12 mumol/L PQ exposed group (P<0.05) . Paraquat 190-192 interleukin 1 beta Mus musculus 112-120 31299241-6 2019 The levels of pro-inflammatory cytokines were determined using ELISA and western blotting assays, showing that paraquat significantly promote the secretion of pro-inflammatory mediators such as tumor necrosis factor alpha (TNF-alpha), interleukin 1beta (IL-1beta) and interleukin 6 (IL-6). Paraquat 111-119 interleukin 1 beta Mus musculus 235-252 31299241-6 2019 The levels of pro-inflammatory cytokines were determined using ELISA and western blotting assays, showing that paraquat significantly promote the secretion of pro-inflammatory mediators such as tumor necrosis factor alpha (TNF-alpha), interleukin 1beta (IL-1beta) and interleukin 6 (IL-6). Paraquat 111-119 interleukin 1 beta Mus musculus 254-262 25633425-6 2015 Furthermore, AA significantly reduced PQ-induced upregulations of inflammatory mediators such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, and IL-8. Paraquat 38-40 interleukin 1 beta Mus musculus 132-154 25338942-9 2015 In the in vitro experiments, IL-1beta and IL-18 secreted from RAW264.7 mouse macrophages treated with paraquat were attenuated by glybenclamide. Paraquat 102-110 interleukin 1 beta Mus musculus 29-37 24893116-6 2014 On day 3, FTY720 administration reduced PQ-induced increases in lung wet weight/body weight (LW/BW), total protein and cytokine levels including interleukin-1beta (IL-1beta), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in bronchoalceolar lavage fluid (BALF). Paraquat 40-42 interleukin 1 beta Mus musculus 145-162 23969119-7 2013 WT mice after PQ exposure displayed deteriorate cardiac function, pathological damages, increased TLR4 mRNA and protein levels as well as myocardial TNF-alpha and IL-1beta levels. Paraquat 14-16 interleukin 1 beta Mus musculus 163-171 23510834-7 2013 RESULTS: Compared with the negative control group, the paraquat poisoning group had significantly increased levels of TNF-alpha, IL-1beta, IL-6, NF-kappaB mRNA, and nuclear NF-kappaB p65 and wet/dry ratio of the lung (P < 0.05). Paraquat 55-63 interleukin 1 beta Mus musculus 129-137 22201039-8 2012 Maneb and paraquat induced the number of degenerating dopaminergic neurons, microglial cells, nitrite content, expressions of IL-1beta, p38 MAPK, NF-kB and TK and caffeine co-treatment reduced the level of such alterations. Paraquat 10-18 interleukin 1 beta Mus musculus 126-134