PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2826141-5 1987 In CTAB-reversed micellar solutions, quenching of the Zn-porphyrin cytochrome c triplet state by ferricyanide and methyl viologen was studied. Paraquat 114-129 cytochrome c, somatic Homo sapiens 67-79 15157803-3 2004 Exposure of cerebellar granule cells to relatively low concentrations of paraquat (5 microM) produces apoptotic cell death with a reduction in mitochondrial cytochrome c content, proteolytic activation and caspase-3 activity increase and DNA fragmentation. Paraquat 73-81 cytochrome c, somatic Homo sapiens 157-169 2835006-4 1988 In the presence of cytochrome c the methylene blue caused a sharp decrease in both paraquat-induced superoxide and hydroxyl radical production. Paraquat 83-91 cytochrome c, somatic Homo sapiens 19-31 2835006-1 1988 Methylene blue competes 100 to 600 times more effectively than paraquat for reduction by three different flavo-containing enzymes; xanthine oxidase, NADH cytochrome c reductase, and NADPH cytochrome c reductase. Paraquat 63-71 cytochrome c, somatic Homo sapiens 154-166 2835006-1 1988 Methylene blue competes 100 to 600 times more effectively than paraquat for reduction by three different flavo-containing enzymes; xanthine oxidase, NADH cytochrome c reductase, and NADPH cytochrome c reductase. Paraquat 63-71 cytochrome c, somatic Homo sapiens 188-200 29355039-2 2019 In this way, FJ1 was shown to reverse the PQ-induced activation of caspase-9 and caspase-3, the increase in Bax/Bcl-2 ratio, and the release of cytochrome c. Paraquat 42-44 cytochrome c, somatic Homo sapiens 144-156 33031936-7 2020 Early high CytoC predicted AKIN2/3 in poisoning with KMnO4/H2C2O4 (AUC-ROC4-8h: 0.81), paraquat (AUC-ROC4-8h: 1.00), and GPSH (AUC-ROC4-8h: 0.91). Paraquat 87-95 cytochrome c, somatic Homo sapiens 11-16 31106605-6 2019 A549 cells were pretreated with 100 microM CA for 24 h and then exposed to 160 microM PQ for 24 h. We found that CA was effective in preventing PQ-induced apoptotic features, including the release of cytochrome c from the mitochondria to cytoplasm, the cleavages of caspase 3 and caspase 9, and the increases in levels of Bcl-2-associated X protein (Bax) and intracellular calcium ions. Paraquat 144-146 cytochrome c, somatic Homo sapiens 200-212 6094249-1 1984 The decay rate of the excited triplet state of Zn cytochrome c was enhanced by electron acceptors including methyl viologen and ferric complexes of cyanide, oxalate, EDTA and cytochrome c at room temperature. Paraquat 108-123 cytochrome c, somatic Homo sapiens 50-62 26649146-5 2016 Furthermore, the activities of Cyc and caspase-9 were found increased significantly at 10 muM of PQ treatment. Paraquat 97-99 cytochrome c, somatic Homo sapiens 31-34 22804935-6 2012 The relative expression of Caspase3, Caspase9 and Cytochrome C genes also increased with the reduced concentrations of RU486, which were the lowest when RU486 concentration was 10(-7) mol/L, as compared with control and PQ exposure groups (P < 0.01 or P < 0.05). Paraquat 220-222 cytochrome c, somatic Homo sapiens 50-62 22491967-7 2012 Surprisingly, paraquat-induced cell death, which harbours some characteristics of apoptosis such as cyt c release and caspase-3 activation, is not modulated by Bcl-2 and caspase inhibitors, suggesting that paraquat also triggers non-apoptotic cell death signals. Paraquat 14-22 cytochrome c, somatic Homo sapiens 100-105 20673835-4 2010 In N27 cells, talipexole inhibited paraquat-induced apoptotic hallmarks such as cytochrome c release, caspase-3 activation, chromatin condensation and externalization of phosphatidilserine. Paraquat 35-43 cytochrome c, somatic Homo sapiens 80-92 16503589-4 2006 The approach was further extended to the determination of conformational changes of cytochrome c molecules attached electrostatically onto a negatively charged SAM during its reduction by the tip-generated methyl viologen monocation. Paraquat 206-221 cytochrome c, somatic Homo sapiens 84-96 18253895-7 2008 By 24 h, paraquat decreased mitochondrial complex I activity and mitochondrial transmembrane potential and induced the release of cytochrome c from mitochondria. Paraquat 9-17 cytochrome c, somatic Homo sapiens 130-142