PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29355039-2	2019	In this way, FJ1 was shown to reverse the PQ-induced activation of caspase-9 and caspase-3, the increase in Bax/Bcl-2 ratio, and the release of cytochrome c.	Paraquat	42-44	cytochrome c, somatic	Homo sapiens	144-156	
2835006-4	1988	In the presence of cytochrome c the methylene blue caused a sharp decrease in both paraquat-induced superoxide and hydroxyl radical production.	Paraquat	83-91	cytochrome c, somatic	Homo sapiens	19-31	
2826141-5	1987	In CTAB-reversed micellar solutions, quenching of the Zn-porphyrin cytochrome c triplet state by ferricyanide and methyl viologen was studied.	Paraquat	114-129	cytochrome c, somatic	Homo sapiens	67-79	
6094249-1	1984	The decay rate of the excited triplet state of Zn cytochrome c was enhanced by electron acceptors including methyl viologen and ferric complexes of cyanide, oxalate, EDTA and cytochrome c at room temperature.	Paraquat	108-123	cytochrome c, somatic	Homo sapiens	50-62	
33031936-7	2020	Early high CytoC predicted AKIN2/3 in poisoning with KMnO4/H2C2O4 (AUC-ROC4-8h: 0.81), paraquat (AUC-ROC4-8h: 1.00), and GPSH (AUC-ROC4-8h: 0.91).	Paraquat	87-95	cytochrome c, somatic	Homo sapiens	11-16	
2835006-1	1988	Methylene blue competes 100 to 600 times more effectively than paraquat for reduction by three different flavo-containing enzymes; xanthine oxidase, NADH cytochrome c reductase, and NADPH cytochrome c reductase.	Paraquat	63-71	cytochrome c, somatic	Homo sapiens	154-166	
2835006-1	1988	Methylene blue competes 100 to 600 times more effectively than paraquat for reduction by three different flavo-containing enzymes; xanthine oxidase, NADH cytochrome c reductase, and NADPH cytochrome c reductase.	Paraquat	63-71	cytochrome c, somatic	Homo sapiens	188-200	
31106605-6	2019	A549 cells were pretreated with 100 microM CA for 24 h and then exposed to 160 microM PQ for 24 h. We found that CA was effective in preventing PQ-induced apoptotic features, including the release of cytochrome c from the mitochondria to cytoplasm, the cleavages of caspase 3 and caspase 9, and the increases in levels of Bcl-2-associated X protein (Bax) and intracellular calcium ions.	Paraquat	144-146	cytochrome c, somatic	Homo sapiens	200-212	
26649146-5	2016	Furthermore, the activities of Cyc and caspase-9 were found increased significantly at 10 muM of PQ treatment.	Paraquat	97-99	cytochrome c, somatic	Homo sapiens	31-34	
22804935-6	2012	The relative expression of Caspase3, Caspase9 and Cytochrome C genes also increased with the reduced concentrations of RU486, which were the lowest when RU486 concentration was 10(-7) mol/L, as compared with control and PQ exposure groups (P < 0.01 or P < 0.05).	Paraquat	220-222	cytochrome c, somatic	Homo sapiens	50-62	
20673835-4	2010	In N27 cells, talipexole inhibited paraquat-induced apoptotic hallmarks such as cytochrome c release, caspase-3 activation, chromatin condensation and externalization of phosphatidilserine.	Paraquat	35-43	cytochrome c, somatic	Homo sapiens	80-92	
18253895-7	2008	By 24 h, paraquat decreased mitochondrial complex I activity and mitochondrial transmembrane potential and induced the release of cytochrome c from mitochondria.	Paraquat	9-17	cytochrome c, somatic	Homo sapiens	130-142	
22491967-7	2012	Surprisingly, paraquat-induced cell death, which harbours some characteristics of apoptosis such as cyt c release and caspase-3 activation, is not modulated by Bcl-2 and caspase inhibitors, suggesting that paraquat also triggers non-apoptotic cell death signals.	Paraquat	14-22	cytochrome c, somatic	Homo sapiens	100-105	
16503589-4	2006	The approach was further extended to the determination of conformational changes of cytochrome c molecules attached electrostatically onto a negatively charged SAM during its reduction by the tip-generated methyl viologen monocation.	Paraquat	206-221	cytochrome c, somatic	Homo sapiens	84-96	
15157803-3	2004	Exposure of cerebellar granule cells to relatively low concentrations of paraquat (5 microM) produces apoptotic cell death with a reduction in mitochondrial cytochrome c content, proteolytic activation and caspase-3 activity increase and DNA fragmentation.	Paraquat	73-81	cytochrome c, somatic	Homo sapiens	157-169