PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9788901-3	1998	Transgenic mice overexpressing three isoforms of superoxide dismutase, catalase, and the cellular glutathione peroxidase (GSHPx-1) in various tissues show an increased tolerance to ischemia-reperfusion heart and brain injury, hyperoxia, cold-induced brain edema, adriamycin, and paraquat toxicity.	Paraquat	279-287	catalase	Mus musculus	71-79	
20937379-10	2010	Taken together, these data revealed that catalase may rescue paraquat-induced myocardial geometric and functional alteration possibly by alleviating JNK-mediated ER stress.	Paraquat	61-69	catalase	Mus musculus	41-49	
18620719-6	2008	Paraquat treatment also resulted in increased expression of HO-1, Cu,Zn-SOD, catalase, GSTP1, GSTA3 and GSTA4.	Paraquat	0-8	catalase	Mus musculus	77-85	
15190189-0	2004	Increased catalase activity in mouse cell mutants resistant to paraquat.	Paraquat	63-71	catalase	Mus musculus	10-18	
11154047-3	2000	Data show that the activities of hepatic SODs and catalase were increased by oral administration of yukmi extracts following PQ pretreatment.	Paraquat	125-127	catalase	Mus musculus	50-58	
20937379-0	2010	Cardiac-specific overexpression of catalase attenuates paraquat-induced myocardial geometric and contractile alteration: role of ER stress.	Paraquat	55-63	catalase	Mus musculus	35-43	
20937379-2	2010	This study examined the influence of cardiac-specific overexpression of catalase, an antioxidant detoxifying H(2)O(2), on paraquat-induced myocardial geometric and functional alterations, with a focus on ER stress.	Paraquat	122-130	catalase	Mus musculus	72-80	
20937379-6	2010	Whereas the catalase transgene itself did not alter myocardial geometry and function, it mitigated or significantly attenuated paraquat-elicited myocardial geometric and functional changes.	Paraquat	127-135	catalase	Mus musculus	12-20	
20937379-7	2010	Paraquat promoted overt apoptosis and ER stress as evidenced by increased caspase-3 activity, apoptosis, and ER stress markers including Bax, Bcl-2, GADD153, calregulin, and phosphorylated JNK, IRE1alpha, and eIF2alpha; all were ablated by the catalase transgene.	Paraquat	0-8	catalase	Mus musculus	244-252	
14759608-5	2004	Hepatocytes and fibroblasts from the Tg(CAT)(+/+) mice were more resistant to hydrogen peroxide-induced cell death but were more sensitive to paraquat and TNFalpha toxicity.	Paraquat	142-150	catalase	Mus musculus	40-43	
10699569-5	2000	It is implied that an early induction of catalase in mice as opposed to rats may account for the resistance of Swiss mice to paraquat toxicity.	Paraquat	125-133	catalase	Mus musculus	41-49	
9482266-7	1998	Antioxidants, such as superoxide dismutase, catalase and promethazine significantly inhibited paraquat-induced lipid peroxidation.	Paraquat	94-102	catalase	Mus musculus	44-52	
8309054-5	1994	In the lung, lipid peroxide concentration decreased significantly and the activities of SOD and CAT increased at 15 hours after injection of paraquat.	Paraquat	141-149	catalase	Mus musculus	96-99	
26362205-4	2015	Consistently, PQ decreased the antioxidant capacity by reducing glutathione peroxidase (GP-X), glutathione-S-transferase (GST) and catalase (CAT) activities, glutathione (GSH) level and total antioxidant capacity (T-AOC), as well as increasing reactive oxygen species (ROS) and thiobarbituric acid reactive substances (TBARS) levels.	Paraquat	14-16	catalase	Mus musculus	131-139	
26362205-4	2015	Consistently, PQ decreased the antioxidant capacity by reducing glutathione peroxidase (GP-X), glutathione-S-transferase (GST) and catalase (CAT) activities, glutathione (GSH) level and total antioxidant capacity (T-AOC), as well as increasing reactive oxygen species (ROS) and thiobarbituric acid reactive substances (TBARS) levels.	Paraquat	14-16	catalase	Mus musculus	141-144	
31264342-7	2019	In addition, both in vitro deficiency and in vivo deficiency of FoxO3 greatly suppressed the activation of antioxidant enzymes including catalase (CAT) and superoxide dismutase 2 (SOD2) in the presence of PQ, which was accompanied by attenuation in cardiac function.	Paraquat	205-207	catalase	Mus musculus	137-145	
31264342-7	2019	In addition, both in vitro deficiency and in vivo deficiency of FoxO3 greatly suppressed the activation of antioxidant enzymes including catalase (CAT) and superoxide dismutase 2 (SOD2) in the presence of PQ, which was accompanied by attenuation in cardiac function.	Paraquat	205-207	catalase	Mus musculus	147-150	
31264342-9	2019	Functionally, overexpression of Cat or Sod2 alleviated the PQ-induced senescence phenotypes in FoxO3-deficient cardiomyocyte cell lines.	Paraquat	59-61	catalase	Mus musculus	32-35	
28480221-5	2017	PQ administration also decreased activity of antioxidases, including superoxide dismutase (SOD), catalase (CAT), and glutathione S-transferases (GSTs), and increased lipid peroxidation as evaluated by malondialdehyde (MDA) levels.	Paraquat	0-2	catalase	Mus musculus	97-105	
28480221-5	2017	PQ administration also decreased activity of antioxidases, including superoxide dismutase (SOD), catalase (CAT), and glutathione S-transferases (GSTs), and increased lipid peroxidation as evaluated by malondialdehyde (MDA) levels.	Paraquat	0-2	catalase	Mus musculus	107-110