PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30296463-0	2018	Bacopa monnieri alleviates paraquat induced toxicity in Drosophila by inhibiting jnk mediated apoptosis through improved mitochondrial function and redox stabilization.	Paraquat	27-35	basket	Drosophila melanogaster	81-84	
35204105-7	2022	Calycosin-fed PQ-exposed flies exhibit significant resistance against PQ-induced mortality and locomotor deficits in terms of reduced oxidative stress, loss of DA neurons, the depletion of dopamine content, and phosphorylated JNK-caspase-3 levels.	Paraquat	14-16	basket	Drosophila melanogaster	226-229	
31481676-6	2019	We found that PQ exposure leads to the activation of the NF-kappaB transcription factor, Relish, and the stress signaling factor JNK, encoded by the gene basket in Drosophila.	Paraquat	14-16	basket	Drosophila melanogaster	129-132	
18538428-6	2008	Moreover, Drosophila fed with (1-200 microM) SP600125, a specific inhibitor of the stress responsive Jun-N-terminal kinase (JNK) signaling, and 20 mM PQ increased survival percentage and movement function (i.e., climbing capability) when compared to flies only treated with PQ.	Paraquat	150-152	basket	Drosophila melanogaster	101-122	
24819147-5	2014	Exposed mth(1) flies exhibit significant resistance against PQ-induced Parkinson"s phenotypes and behavior in terms of oxidative stress, dopaminergic neuronal degeneration, locomotor performance, dopamine content, phosphorylated JNK, pFOXO, Hid, and cleaved caspase-3 levels.	Paraquat	60-62	basket	Drosophila melanogaster	229-232	
24819147-7	2014	The study suggests that lesser activation of JNK-mediated apoptosis in dopaminergic neurons of exposed mth(1) flies protects the organism from PQ-induced damage, which may be causally linked to a common mechanism for PQ-induced neurodegeneration.	Paraquat	143-145	basket	Drosophila melanogaster	45-48	
24819147-7	2014	The study suggests that lesser activation of JNK-mediated apoptosis in dopaminergic neurons of exposed mth(1) flies protects the organism from PQ-induced damage, which may be causally linked to a common mechanism for PQ-induced neurodegeneration.	Paraquat	217-219	basket	Drosophila melanogaster	45-48	
25474322-7	2014	By genetic manipulations, we demonstrate that dMRP4 is required for JNK (c-Jun NH2-terminal kinase) activation during paraquat challenge and for basal transcription of some JNK target genes under normal condition.	Paraquat	118-126	basket	Drosophila melanogaster	68-71	
25474322-7	2014	By genetic manipulations, we demonstrate that dMRP4 is required for JNK (c-Jun NH2-terminal kinase) activation during paraquat challenge and for basal transcription of some JNK target genes under normal condition.	Paraquat	118-126	basket	Drosophila melanogaster	73-98	
24887138-0	2014	Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson"s disease.	Paraquat	42-50	basket	Drosophila melanogaster	91-94	
19720829-6	2009	Neuronal expression of Jafrac1 also significantly reduced ROS levels, restored mitochondrial function, and attenuated JNK activation caused by paraquat.	Paraquat	143-151	basket	Drosophila melanogaster	118-121	
18538428-6	2008	Moreover, Drosophila fed with (1-200 microM) SP600125, a specific inhibitor of the stress responsive Jun-N-terminal kinase (JNK) signaling, and 20 mM PQ increased survival percentage and movement function (i.e., climbing capability) when compared to flies only treated with PQ.	Paraquat	150-152	basket	Drosophila melanogaster	124-127