PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12654481-7	2003	The paraquat-mediated gene or protein expression of proapoptotic Bax, Bcl-w, and Bcl-X(S), cell survival/death factors GADD45, MDM2, c-Myc, and caspase-3 was upregulated, but that of antiapoptotic Bcl-2 was downregulated in the GPX1-/- mice vs. the WT mice.	Paraquat	4-12	BCL2-associated X protein	Mus musculus	65-68	
15824117-8	2005	Even a single injection of paraquat + maneb in the non-transgenic treated group modulated several key pro- and anti-apoptotic proteins, including Bax, Bad, Bcl-xL, and upstream stress-induced cascade.	Paraquat	27-35	BCL2-associated X protein	Mus musculus	146-149	
30171970-8	2018	In addition, PQ reduced cellular beta-catenin, p-GSK-3beta, and cyclin-D1 and increased the radio of Bax/Bcl2.	Paraquat	13-15	BCL2-associated X protein	Mus musculus	101-104	
28115273-9	2017	Paraquat triggered O2- production, lipid peroxidation and apoptosis as evidenced by increased DHE staining, 4-HNE, caspase-3 activity, Bax and reduced Bcl-2 levels in association with unchanged ER stress.	Paraquat	0-8	BCL2-associated X protein	Mus musculus	135-138	
28480221-6	2017	PQ exposure induced upregulation of the proapoptotic gene Bax and downregulation of the antiapoptotic gene Bcl-2, leading to marked cell apoptosis in the lung tissues.	Paraquat	0-2	BCL2-associated X protein	Mus musculus	58-61	
20937379-7	2010	Paraquat promoted overt apoptosis and ER stress as evidenced by increased caspase-3 activity, apoptosis, and ER stress markers including Bax, Bcl-2, GADD153, calregulin, and phosphorylated JNK, IRE1alpha, and eIF2alpha; all were ablated by the catalase transgene.	Paraquat	0-8	BCL2-associated X protein	Mus musculus	137-140	
29201275-11	2017	Furthermore, Res and/or MK reversed PQ-induced apoptosis assessed by differential expression of p53, Bax, and Bcl-2.	Paraquat	36-38	BCL2-associated X protein	Mus musculus	101-104	
25111661-6	2014	PQ also induced more apoptosis in pneumocytes from MT(-/-) mice, and the expressions of apoptosis-related proteins Bax, Bcl-2, cleaved-caspase-3, and the ratio of Bax/Bcl-2 were all more significantly increased in PQ-treated MT(-/-) mice.	Paraquat	0-2	BCL2-associated X protein	Mus musculus	115-118	
25111661-6	2014	PQ also induced more apoptosis in pneumocytes from MT(-/-) mice, and the expressions of apoptosis-related proteins Bax, Bcl-2, cleaved-caspase-3, and the ratio of Bax/Bcl-2 were all more significantly increased in PQ-treated MT(-/-) mice.	Paraquat	0-2	BCL2-associated X protein	Mus musculus	163-166