PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20455021-7 2010 MB- and PQ-treatment induced nitrite content, expressions of iNOS mRNA and protein and lipid peroxidation as compared with respective controls. Paraquat 8-10 nitric oxide synthase 2, inducible Mus musculus 61-65 20455021-9 2010 Genistein, SB202190 and PDTC reduced the expression of iNOS mRNA, nitrite content and lipid peroxidation in MB- and PQ-treated mouse striatum. Paraquat 116-118 nitric oxide synthase 2, inducible Mus musculus 55-59 20455021-10 2010 The results obtained demonstrate that nitric oxide contributes to an increase of MB- and PQ-induced lipid peroxidation in mouse striatum and tyrosine kinase, p38 MAPK and NF-kB regulate iNOS expression. Paraquat 89-91 nitric oxide synthase 2, inducible Mus musculus 186-190 34863858-5 2022 The results showed that the cell activation markers (iNOS and CD206) of BV-2 cells were increased after PQ treatment, suggesting that BV-2 microglia were activated. Paraquat 104-106 nitric oxide synthase 2, inducible Mus musculus 53-57 32375810-14 2020 Moreover, reduced reactive oxygen species production, NADPH oxidase, and inducible nitric oxide synthase expressions as well as 4-hydroxynonenal and malondialdehyde levels were detected in combined glybenclamide and paraquat and maneb-treated mice compared with paraquat and maneb alone group. Paraquat 216-224 nitric oxide synthase 2, inducible Mus musculus 73-104 34052309-8 2021 Finally, the increased superoxide production, lipid peroxidation, protein levels of NADPH oxidase 2 (NOX2) and inducible nitric oxide synthase (iNOS) induced by paraquat and maneb were all attenuated by glibenclamide. Paraquat 161-169 nitric oxide synthase 2, inducible Mus musculus 111-142 34052309-8 2021 Finally, the increased superoxide production, lipid peroxidation, protein levels of NADPH oxidase 2 (NOX2) and inducible nitric oxide synthase (iNOS) induced by paraquat and maneb were all attenuated by glibenclamide. Paraquat 161-169 nitric oxide synthase 2, inducible Mus musculus 144-148 33287470-13 2020 Compared with the control group, the PQ group showed a decrease in the number of Nissl body in the hippocampus and substantia nigra (P<0.05) , a decrease in the number of NeuN and TH positive cells in the substantia nigra (P<0.05) , with a large number of alpha-syn deposition, Iba-1 activation of microglia cells, and an increase in the expression of inflammatory factors (IL-1beta, iNOS) in the hippocampus and substantia nigra (P<0.05) . Paraquat 37-39 nitric oxide synthase 2, inducible Mus musculus 384-388 28249220-7 2017 In addition, the inflammatory responses induced by paraquat were inhibited after treatment with chloroquine, as indicated by the decreased number of leukocytes, the reduced levels of TNF-alpha, IL-1beta and IL-6 in the bronchoalveolar lavage fluid, the reduced NO content, and downregulation of iNOS expression in lung tissues. Paraquat 51-59 nitric oxide synthase 2, inducible Mus musculus 295-299 31937024-12 2019 Western blot showed that compared with 0 mumol/L PQ group, the expression levels of M1 markers TNF-alpha, IL-6, IL-1beta, iNOS and CD86 were significantly increased in 0.03 and 0.06 mumol/L PQ exposed group, while the expression levels of M2 markers Arg-1 and CD206 protein were decreased in 0.06 and 0.12 mumol/L PQ exposed group (P<0.05) . Paraquat 49-51 nitric oxide synthase 2, inducible Mus musculus 122-126 31937024-12 2019 Western blot showed that compared with 0 mumol/L PQ group, the expression levels of M1 markers TNF-alpha, IL-6, IL-1beta, iNOS and CD86 were significantly increased in 0.03 and 0.06 mumol/L PQ exposed group, while the expression levels of M2 markers Arg-1 and CD206 protein were decreased in 0.06 and 0.12 mumol/L PQ exposed group (P<0.05) . Paraquat 190-192 nitric oxide synthase 2, inducible Mus musculus 122-126 31937024-12 2019 Western blot showed that compared with 0 mumol/L PQ group, the expression levels of M1 markers TNF-alpha, IL-6, IL-1beta, iNOS and CD86 were significantly increased in 0.03 and 0.06 mumol/L PQ exposed group, while the expression levels of M2 markers Arg-1 and CD206 protein were decreased in 0.06 and 0.12 mumol/L PQ exposed group (P<0.05) . Paraquat 190-192 nitric oxide synthase 2, inducible Mus musculus 122-126 27919828-10 2017 PQ-treatment increased nitrite content, expression of iNOS and lipid peroxidation compared to respective controls. Paraquat 0-2 nitric oxide synthase 2, inducible Mus musculus 54-58 25952542-5 2016 Coexposure to Maneb and paraquat for 6 weeks resulted in active microgliosis, NADPH oxidase activation, and inducible nitric oxide synthase (iNOS) induction, which culminated in protein radical formation in the midbrains of mice. Paraquat 24-32 nitric oxide synthase 2, inducible Mus musculus 108-139 25952542-5 2016 Coexposure to Maneb and paraquat for 6 weeks resulted in active microgliosis, NADPH oxidase activation, and inducible nitric oxide synthase (iNOS) induction, which culminated in protein radical formation in the midbrains of mice. Paraquat 24-32 nitric oxide synthase 2, inducible Mus musculus 141-145