PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32527420-8	2020	Also, QNLC meaningfully restored MMP reduction, lysosomal membrane destabilization, and lipid peroxidation and were capable of preventing PQ-treated change in Bax and Bcl2 gene expression.	Paraquat	138-140	BCL2 apoptosis regulator	Homo sapiens	167-171	
34394837-13	2021	Meanwhile, Bcl2, Bax, and p-38 were involved in apoptosis induced by PQ.	Paraquat	69-71	BCL2 apoptosis regulator	Homo sapiens	11-15	
34394837-15	2021	Bcl2/Bax and P-p38/p38 pathways mediated the cross-talk between ferroptosis and apoptosis induced by PQ.	Paraquat	101-103	BCL2 apoptosis regulator	Homo sapiens	0-4	
32251495-6	2020	When compared with PQ group, the cells in both SP600125+PQ group and SB203580+PQ group had significantly increased viability and level of anti-apoptotic protein Bcl-2; and had decreased apoptotic rates, decreased levels of caspase-3 and -9, and decreased level of pro-apoptotic protein Bax.	Paraquat	56-58	BCL2 apoptosis regulator	Homo sapiens	161-166	
32251495-6	2020	When compared with PQ group, the cells in both SP600125+PQ group and SB203580+PQ group had significantly increased viability and level of anti-apoptotic protein Bcl-2; and had decreased apoptotic rates, decreased levels of caspase-3 and -9, and decreased level of pro-apoptotic protein Bax.	Paraquat	56-58	BCL2 apoptosis regulator	Homo sapiens	161-166	
29294513-8	2017	PQ dramatically induced HK-2 apoptosis evidenced by increasing expressions of caspase-9, caspase-3 and Bax, while decreasing Bcl-2 level.	Paraquat	0-2	BCL2 apoptosis regulator	Homo sapiens	125-130	
23954820-4	2013	Mitochondria-mediated apoptosis pathway contributed importantly to PQ-induced apoptosis, as revealed by the activation of caspase-3/-9, cleavage of PARP, depletion of mitochondrial membrane potential regulated by Bcl-2 family members, and overproduction of reactive oxygen species, which were also effectively blocked by CF.	Paraquat	67-69	BCL2 apoptosis regulator	Homo sapiens	213-218	
31485636-9	2019	Following treatment with curcumin, PQ-induced increases in ROS levels and apoptosis were significantly attenuated, and Bcl-2 expression levels were upregulated, whereas those of Bax were downregulated.	Paraquat	35-37	BCL2 apoptosis regulator	Homo sapiens	119-124	
29355039-2	2019	In this way, FJ1 was shown to reverse the PQ-induced activation of caspase-9 and caspase-3, the increase in Bax/Bcl-2 ratio, and the release of cytochrome c.	Paraquat	42-44	BCL2 apoptosis regulator	Homo sapiens	112-117	
29495168-12	2018	(4) Compared with the normal control group, Bcl-2 protein expression in PQ group was significantly decreased and BAX protein expression in PQ group was significantly increased (P<0.05) ; compared with PQ group, Bcl-2 protein expression in PQ+XBJ group was significantly increased, BAX protein expression in PQ+XBJ group was significantly decreased (P<0.05).	Paraquat	72-74	BCL2 apoptosis regulator	Homo sapiens	44-49	
29495168-12	2018	(4) Compared with the normal control group, Bcl-2 protein expression in PQ group was significantly decreased and BAX protein expression in PQ group was significantly increased (P<0.05) ; compared with PQ group, Bcl-2 protein expression in PQ+XBJ group was significantly increased, BAX protein expression in PQ+XBJ group was significantly decreased (P<0.05).	Paraquat	139-141	BCL2 apoptosis regulator	Homo sapiens	214-219	
29495168-12	2018	(4) Compared with the normal control group, Bcl-2 protein expression in PQ group was significantly decreased and BAX protein expression in PQ group was significantly increased (P<0.05) ; compared with PQ group, Bcl-2 protein expression in PQ+XBJ group was significantly increased, BAX protein expression in PQ+XBJ group was significantly decreased (P<0.05).	Paraquat	139-141	BCL2 apoptosis regulator	Homo sapiens	214-219	
18715146-3	2009	Oxidative stress induced by the neurotoxins MPTP, paraquat, maneb, and rotenone causes lipid peroxidation and protein misfolding that affects cell death through members of the Bcl-2 family.	Paraquat	50-58	BCL2 apoptosis regulator	Homo sapiens	176-181