PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33345848-0	2021	Off-label use of chloroquine, hydroxychloroquine, azithromycin and lopinavir/ritonavir in COVID-19 risks prolonging the QT interval by targeting the hERG channel.	Azithromycin	50-62	ETS transcription factor ERG	Homo sapiens	149-153	
33674391-5	2021	Here we study the effects of chloroquine, hydroxychloroquine, azithromycin, and remdesivir on hERG channels.	Azithromycin	62-74	ETS transcription factor ERG	Homo sapiens	94-98	
33674391-10	2021	Significance Statement This work demonstrates that among off-label potential COVID-19 treatment drugs chloroquine, hydroxychloroquine, azithromycin, and remdesivir, the former two drugs block hERG potassium channels while the latter two drugs do not.	Azithromycin	135-147	ETS transcription factor ERG	Homo sapiens	192-196	
33345848-3	2021	Clinically, however, many drugs, including those currently used in COVID-19, such as chloroquine, hydroxychloroquine, azithromycin, and lopinavir/ritonavir, may cause cardiotoxicity by acting on cardiac potassium channels and the hERG channel through their off-target effects.	Azithromycin	118-130	ETS transcription factor ERG	Homo sapiens	230-234	
17088870-5	2006	EXPERIMENTAL APPROACH & KEY RESULTS: In transfected HEK cells, the IC(50)s for I (hERG) were 45+/-6 and 856+/-259 microg ml(-1) for moxifloxacin and azithromycin, respectively.	Azithromycin	153-165	ETS transcription factor ERG	Homo sapiens	86-90	
25976224-8	2015	(1) Azithromycin reduced hERG currents by accelerated channel inactivation.	Azithromycin	4-16	ETS transcription factor ERG	Homo sapiens	25-29	
25976224-9	2015	(2) The combination of Berberine with Azithromycin reduced hERG currents, producing an inhibitive effect stronger than use of a single drug alone, due to the high binding affinity for the onset of inactivation.	Azithromycin	38-50	ETS transcription factor ERG	Homo sapiens	59-63